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• W2000720719 abstract "Fixed-dose combination of sitagliptin and metformin for the treatment of type 2 diabetes Jonathan K ReynoldsWashington State University, College of Pharmacy, Pullman, WA, USAAbstract: JanumetTM, a fixed dose combination of sitagliptin/metformin HCL manufactured by Merck Pharmaceuticals, has received US Food and Drug Administration approval for treatment of patients with type 2 diabetes, that are inadequately controlled, either by sitagliptin or metformin alone or together in free-dose combination form. Sitagliptin, an inhibitor of the enzyme DDP-4, assists patients with type 2 diabetes mellitus to achieve glycemic control. It has been shown to be safe and effective at 100 mg daily doses. The effect of giving sitagliptin in combination with metformin is thought to have a complimentary and possibly additive effect on glycemic control.Keywords: sitagliptin, metformin, fixed-dose combination, dipeptidyl peptidase-4 inhibitor, DPP-4 inhibitor" @default.
• W2000720719 created "2016-06-24" @default.
• W2000720719 creator A5085561756 @default.
• W2000720719 date "2009-07-01" @default.
• W2000720719 modified "2023-10-13" @default.
• W2000720719 title "Fixed-dose combination of sitagliptin and metformin for the treatment of type 2 diabetes" @default.
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• W2000720719 doi "https://doi.org/10.2147/dmsott.s4637" @default.
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