Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000721102> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2000721102 endingPage "252" @default.
- W2000721102 startingPage "251" @default.
- W2000721102 abstract "The [Pt(9-methyl-guanine)4]2+ cation is the first example of a Pt2+ compound to have four purine bases as ligands. This compound is especially interesting as it was suggested earlier that the anti-tumor drug cis-dichlorodiammineplatinum(II) could lose all four ligands in order to interact with the purine bases of the DNA double helix [1]. The title compound was prepared by heating K2PtCl4 with excess 9-methylguanine (ratio 1:6) under reflux for several hours. The reaction mixture was separated by preparative reverse-phase high-performance liquid chromatography to remove excess ligand and some minor impurities possibly due to the formation of other Pt-guanine complexes. [Pt(9-Methylguanine)4]2+Cl−(CF3COOH)− crystallizes as colorless bricks in the triclinic space group P1, with a = 16.234(8) Å, b = 13.475(7) Å, c = 10.856(5) Å, α = 103.80(4)°, β = 91.40(4)°, γ = 115.50(3)°, Z = 2. The structure consists of a Pt(9-MeG)2+4 cation in which each purine ligand is coordinated through its N(7) nitrogen atom (Fig. 1) to result in a PtN4-square plane. The purine ligands are in the usual alternating head to tail arrangement with the adjacent C(6)O(6) pointing in opposite directions. The average PtN distance is 2.036 Å. The current R-value is 7.8% with 4475 independent reflections." @default.
- W2000721102 created "2016-06-24" @default.
- W2000721102 creator A5014671600 @default.
- W2000721102 creator A5088756424 @default.
- W2000721102 date "1983-01-01" @default.
- W2000721102 modified "2023-09-26" @default.
- W2000721102 title "Crystal structure of the [Pt(9-methylguanine)4]2+ cation" @default.
- W2000721102 cites W1997725543 @default.
- W2000721102 cites W2045768558 @default.
- W2000721102 doi "https://doi.org/10.1016/s0020-1693(00)95293-9" @default.
- W2000721102 hasPublicationYear "1983" @default.
- W2000721102 type Work @default.
- W2000721102 sameAs 2000721102 @default.
- W2000721102 citedByCount "11" @default.
- W2000721102 countsByYear W20007211022016 @default.
- W2000721102 crossrefType "journal-article" @default.
- W2000721102 hasAuthorship W2000721102A5014671600 @default.
- W2000721102 hasAuthorship W2000721102A5088756424 @default.
- W2000721102 hasConcept C104317684 @default.
- W2000721102 hasConcept C115624301 @default.
- W2000721102 hasConcept C116569031 @default.
- W2000721102 hasConcept C170493617 @default.
- W2000721102 hasConcept C178790620 @default.
- W2000721102 hasConcept C185592680 @default.
- W2000721102 hasConcept C2778301229 @default.
- W2000721102 hasConcept C2780378348 @default.
- W2000721102 hasConcept C42228675 @default.
- W2000721102 hasConcept C512185932 @default.
- W2000721102 hasConcept C55493867 @default.
- W2000721102 hasConcept C71240020 @default.
- W2000721102 hasConcept C8010536 @default.
- W2000721102 hasConceptScore W2000721102C104317684 @default.
- W2000721102 hasConceptScore W2000721102C115624301 @default.
- W2000721102 hasConceptScore W2000721102C116569031 @default.
- W2000721102 hasConceptScore W2000721102C170493617 @default.
- W2000721102 hasConceptScore W2000721102C178790620 @default.
- W2000721102 hasConceptScore W2000721102C185592680 @default.
- W2000721102 hasConceptScore W2000721102C2778301229 @default.
- W2000721102 hasConceptScore W2000721102C2780378348 @default.
- W2000721102 hasConceptScore W2000721102C42228675 @default.
- W2000721102 hasConceptScore W2000721102C512185932 @default.
- W2000721102 hasConceptScore W2000721102C55493867 @default.
- W2000721102 hasConceptScore W2000721102C71240020 @default.
- W2000721102 hasConceptScore W2000721102C8010536 @default.
- W2000721102 hasLocation W20007211021 @default.
- W2000721102 hasOpenAccess W2000721102 @default.
- W2000721102 hasPrimaryLocation W20007211021 @default.
- W2000721102 hasRelatedWork W1621575739 @default.
- W2000721102 hasRelatedWork W1969790004 @default.
- W2000721102 hasRelatedWork W1970564572 @default.
- W2000721102 hasRelatedWork W1989359090 @default.
- W2000721102 hasRelatedWork W1992002288 @default.
- W2000721102 hasRelatedWork W2033649299 @default.
- W2000721102 hasRelatedWork W2085807352 @default.
- W2000721102 hasRelatedWork W2156164463 @default.
- W2000721102 hasRelatedWork W2321265370 @default.
- W2000721102 hasRelatedWork W2372298381 @default.
- W2000721102 hasVolume "79" @default.
- W2000721102 isParatext "false" @default.
- W2000721102 isRetracted "false" @default.
- W2000721102 magId "2000721102" @default.
- W2000721102 workType "article" @default.