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• W2000721825 abstract "Feeding behavior is regulated by feeding-related peptides in the hypothalamus. The neurons of the arcuate nucleus (ARC), which produces feeding-related peptides, develop and function by three weeks of age in rodents. Because rodents are weaned at three weeks, we studied whether the process of weaning is involved in the development of ARC neurons using monosodium glutamate. Rat pups injected neonatally with monosodium glutamate ingested a large amount of mother's milk at weaning. Monosodium glutamate treatment induced a decrease in the number of ARC cells and mRNA levels of neuropeptide Y and agouti-related protein in the hypothalamus. The alteration of milk consumption following monosodium glutamate treatment appears to cause failure of ARC neuron development and neuropeptide expression." @default.
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• W2000721825 date "2009-01-01" @default.
• W2000721825 modified "2023-09-23" @default.
• W2000721825 title "Association of the Suckling-Weaning Transition with Development of the Hypothalamic Arcuate Nucleus Neurons in Rat Pups" @default.
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• W2000721825 doi "https://doi.org/10.1538/expanim.58.61" @default.
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