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• W2000721848 abstract "The Total (Peroxyl) Radical-trapping Antioxidant Parameter (TRAP) of six freshly prepared human plasma samples and 45 frozen plasma samples has been determined. It is shown that contributions from urate (35–65%), plasma proteins (10–50%), ascorbate (0–24%) and vitamin E (5–10%) to TRAP account for all of the peroxyl radical-trapping antioxidant activity in the majority of the samples. The changes in concentrations of the plasma antioxidants during peroxyl radical attack show that first line of defense is provided by the plasma sulfhydryl group, even urate being spared during the initial stages of the reaction. The modes of action of all of these plasma antioxidants and possible interactions between them are discussed, with particular emphasis on the abilities of the water-soluble antioxidants to regenerate or spare the only lipid-soluble antioxidant, vitamin E." @default.
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• W2000721848 date "1987-06-01" @default.
• W2000721848 modified "2023-10-16" @default.
• W2000721848 title "The relative contributions of vitamin E, urate, ascorbate and proteins to the total peroxyl radical-trapping antioxidant activity of human blood plasma" @default.
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• W2000721848 doi "https://doi.org/10.1016/0304-4165(87)90155-3" @default.
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