FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000730704> ?p ?o ?g. }

• W2000730704 endingPage "1337" @default.
• W2000730704 startingPage "1333" @default.
• W2000730704 abstract "Autologous blood clot was injected into six dogs to produce a graduated decrease in cardiac output (CO). The effects of an infusion of norepinephrine, titrated to specific end points, were recorded before embolization and at two levels of pulmonary hypertension. Simultaneous measurements of systemic and renal hemodynamics were made. Sequential blood clot injection increased (p<.01) pulmonary vascular resistance (PVR) from 1.3 to 13 to 33 mm Hg•L-1•min and reduced CO 45 percent and 75 percent (p<.01). Norepinephrine increased both stroke volume and CO (p<.01) in each condition and did not increase PVR. Since the biventricular filling pressures remained constant or fell slightly with norepinephrine, the increase in CO is best explained by an improvement in pump performance. There was no deterioration in renal blood flow or creatinine clearance with norepinephrine. The data suggested that in this model of right ventricular dysfunction, norepinephrine consistently improved myocardial performance without provoking further vasoconstriction in either the pulmonary or renal circulations. Autologous blood clot was injected into six dogs to produce a graduated decrease in cardiac output (CO). The effects of an infusion of norepinephrine, titrated to specific end points, were recorded before embolization and at two levels of pulmonary hypertension. Simultaneous measurements of systemic and renal hemodynamics were made. Sequential blood clot injection increased (p<.01) pulmonary vascular resistance (PVR) from 1.3 to 13 to 33 mm Hg•L-1•min and reduced CO 45 percent and 75 percent (p<.01). Norepinephrine increased both stroke volume and CO (p<.01) in each condition and did not increase PVR. Since the biventricular filling pressures remained constant or fell slightly with norepinephrine, the increase in CO is best explained by an improvement in pump performance. There was no deterioration in renal blood flow or creatinine clearance with norepinephrine. The data suggested that in this model of right ventricular dysfunction, norepinephrine consistently improved myocardial performance without provoking further vasoconstriction in either the pulmonary or renal circulations. Is Levophed Lethal?CHESTVol. 95Issue 6PreviewThe thin-walled right ventricle (RV) has received little attention in the past compared with its muscular neighbor, the left ventricle (LV).1,2 Recently, the availability of better bedside techniques to study RV function, such as 2D echocardiography, radionuclear angiography, and the fast-response thermistor catheter, have allowed us to understand the role of the RV in many clinical settings. RV dysfunction has been implicated in a spectrum of cardiopulmonary disorders including pulmonary embolism, COPD, ARDS, application of PEEP, sepsis, myocardial contusion, and response to cardiopulmonary bypass. Full-Text PDF" @default.
• W2000730704 created "2016-06-24" @default.
• W2000730704 creator A5007473658 @default.
• W2000730704 creator A5030726149 @default.
• W2000730704 creator A5030965821 @default.
• W2000730704 creator A5066628796 @default.
• W2000730704 creator A5079428060 @default.
• W2000730704 date "1989-06-01" @default.
• W2000730704 modified "2023-09-25" @default.
• W2000730704 title "The Cardiopulmonary and Renal Hemodynamic Effects of Norepinephrine in Canine Pulmonary Embolism" @default.
• W2000730704 cites W1521591748 @default.
• W2000730704 cites W1971330063 @default.
• W2000730704 cites W1976076311 @default.
• W2000730704 cites W1984314126 @default.
• W2000730704 cites W1995794429 @default.
• W2000730704 cites W2003373752 @default.
• W2000730704 cites W2008296938 @default.
• W2000730704 cites W2015373223 @default.
• W2000730704 cites W2020900565 @default.
• W2000730704 cites W2029730301 @default.
• W2000730704 cites W2034427990 @default.
• W2000730704 cites W2065236350 @default.
• W2000730704 cites W2065350435 @default.
• W2000730704 cites W2066689305 @default.
• W2000730704 cites W2114050269 @default.
• W2000730704 cites W2135073519 @default.
• W2000730704 cites W2137676614 @default.
• W2000730704 cites W2160834796 @default.
• W2000730704 cites W2165562548 @default.
• W2000730704 cites W2422269837 @default.
• W2000730704 cites W4301019036 @default.
• W2000730704 doi "https://doi.org/10.1378/chest.95.6.1333" @default.
• W2000730704 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2721272" @default.
• W2000730704 hasPublicationYear "1989" @default.
• W2000730704 type Work @default.
• W2000730704 sameAs 2000730704 @default.
• W2000730704 citedByCount "61" @default.
• W2000730704 countsByYear W20007307042012 @default.
• W2000730704 countsByYear W20007307042013 @default.
• W2000730704 countsByYear W20007307042014 @default.
• W2000730704 countsByYear W20007307042015 @default.
• W2000730704 countsByYear W20007307042016 @default.
• W2000730704 countsByYear W20007307042018 @default.
• W2000730704 countsByYear W20007307042019 @default.
• W2000730704 countsByYear W20007307042020 @default.
• W2000730704 countsByYear W20007307042021 @default.
• W2000730704 countsByYear W20007307042023 @default.
• W2000730704 crossrefType "journal-article" @default.
• W2000730704 hasAuthorship W2000730704A5007473658 @default.
• W2000730704 hasAuthorship W2000730704A5030726149 @default.
• W2000730704 hasAuthorship W2000730704A5030965821 @default.
• W2000730704 hasAuthorship W2000730704A5066628796 @default.
• W2000730704 hasAuthorship W2000730704A5079428060 @default.
• W2000730704 hasConcept C126322002 @default.
• W2000730704 hasConcept C139940330 @default.
• W2000730704 hasConcept C142225936 @default.
• W2000730704 hasConcept C164705383 @default.
• W2000730704 hasConcept C178853913 @default.
• W2000730704 hasConcept C2778514916 @default.
• W2000730704 hasConcept C37557685 @default.
• W2000730704 hasConcept C42219234 @default.
• W2000730704 hasConcept C513476851 @default.
• W2000730704 hasConcept C58245268 @default.
• W2000730704 hasConcept C71924100 @default.
• W2000730704 hasConceptScore W2000730704C126322002 @default.
• W2000730704 hasConceptScore W2000730704C139940330 @default.
• W2000730704 hasConceptScore W2000730704C142225936 @default.
• W2000730704 hasConceptScore W2000730704C164705383 @default.
• W2000730704 hasConceptScore W2000730704C178853913 @default.
• W2000730704 hasConceptScore W2000730704C2778514916 @default.
• W2000730704 hasConceptScore W2000730704C37557685 @default.
• W2000730704 hasConceptScore W2000730704C42219234 @default.
• W2000730704 hasConceptScore W2000730704C513476851 @default.
• W2000730704 hasConceptScore W2000730704C58245268 @default.
• W2000730704 hasConceptScore W2000730704C71924100 @default.
• W2000730704 hasIssue "6" @default.
• W2000730704 hasLocation W20007307041 @default.
• W2000730704 hasLocation W20007307042 @default.
• W2000730704 hasOpenAccess W2000730704 @default.
• W2000730704 hasPrimaryLocation W20007307041 @default.
• W2000730704 hasRelatedWork W1504377109 @default.
• W2000730704 hasRelatedWork W2000730704 @default.
• W2000730704 hasRelatedWork W2050120301 @default.
• W2000730704 hasRelatedWork W2051164743 @default.
• W2000730704 hasRelatedWork W2054514185 @default.
• W2000730704 hasRelatedWork W2056069181 @default.
• W2000730704 hasRelatedWork W2086295978 @default.
• W2000730704 hasRelatedWork W2177349278 @default.
• W2000730704 hasRelatedWork W2334173305 @default.
• W2000730704 hasRelatedWork W2406854482 @default.
• W2000730704 hasVolume "95" @default.
• W2000730704 isParatext "false" @default.
• W2000730704 isRetracted "false" @default.
• W2000730704 magId "2000730704" @default.
• W2000730704 workType "article" @default.