Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000735805> ?p ?o ?g. }
- W2000735805 endingPage "590" @default.
- W2000735805 startingPage "582" @default.
- W2000735805 abstract "Recent studies have found that cardiac stem cells (CSCs) are present in the adult heart. CSCs play an important role in maintaining the balance of the number of myocardial cells. The purpose of this study was to examine characteristics of human CSCs and their correlation with clinical characteristics of patients. We collected heart auricles of 105 patients (age range, 1–78 years; mean, 55.6 ± 17.0 years) undergoing cardiac surgery to obtain CSCs. We assayed the percentage of c-kit positive (c-kit + ) CSCs with flow cytometry. Plasma N ɛ -(carboxymethyl)lysine (CML) concentrations were measured by enzyme-linked immunosorbent assay. The percentage of c-kit + CSCs was 4.96 ± 3.12% (0.98–17.17%), and this was significantly negatively correlated with age, the presence of diabetes mellitus (DM) and coronary heart disease (CHD) ( r values were −0.797 [ P < 0.01], −0.500 [ P < 0.01] and −0.250 [ P = 0.011], respectively). The percentage of c-kit + CSCs was significantly negatively correlated with CML concentrations ( r = −0.859, P < 0.01). The percentage of c-kit + CSCs decreases with ageing and is further decreased in patients with DM and/or CHD. Furthermore, plasma CML concentrations may have potential as an indicator of the number of c-kit + CSCs." @default.
- W2000735805 created "2016-06-24" @default.
- W2000735805 creator A5062875328 @default.
- W2000735805 creator A5064917249 @default.
- W2000735805 creator A5067818460 @default.
- W2000735805 creator A5071112818 @default.
- W2000735805 creator A5077889482 @default.
- W2000735805 creator A5078189216 @default.
- W2000735805 date "2013-11-06" @default.
- W2000735805 modified "2023-10-15" @default.
- W2000735805 title "The influence of disease and age on human cardiac stem cells" @default.
- W2000735805 cites W1556333628 @default.
- W2000735805 cites W1963756072 @default.
- W2000735805 cites W1966347073 @default.
- W2000735805 cites W1971858639 @default.
- W2000735805 cites W1972812055 @default.
- W2000735805 cites W1972943373 @default.
- W2000735805 cites W1981730769 @default.
- W2000735805 cites W1987934876 @default.
- W2000735805 cites W1993396023 @default.
- W2000735805 cites W1999631700 @default.
- W2000735805 cites W2002073421 @default.
- W2000735805 cites W2015544059 @default.
- W2000735805 cites W2020857408 @default.
- W2000735805 cites W2026749151 @default.
- W2000735805 cites W2028036560 @default.
- W2000735805 cites W2036385196 @default.
- W2000735805 cites W2046027917 @default.
- W2000735805 cites W2049796621 @default.
- W2000735805 cites W2051251503 @default.
- W2000735805 cites W2060610551 @default.
- W2000735805 cites W2064046486 @default.
- W2000735805 cites W2065012620 @default.
- W2000735805 cites W2065171831 @default.
- W2000735805 cites W2070793750 @default.
- W2000735805 cites W2072004228 @default.
- W2000735805 cites W2078540617 @default.
- W2000735805 cites W2080539468 @default.
- W2000735805 cites W2085408320 @default.
- W2000735805 cites W2089878313 @default.
- W2000735805 cites W2096391100 @default.
- W2000735805 cites W2097474009 @default.
- W2000735805 cites W2101986300 @default.
- W2000735805 cites W2105956218 @default.
- W2000735805 cites W2106217169 @default.
- W2000735805 cites W2108448809 @default.
- W2000735805 cites W2108747532 @default.
- W2000735805 cites W2108879443 @default.
- W2000735805 cites W2113074426 @default.
- W2000735805 cites W2113273302 @default.
- W2000735805 cites W2116502734 @default.
- W2000735805 cites W2116605287 @default.
- W2000735805 cites W2122059700 @default.
- W2000735805 cites W2132735690 @default.
- W2000735805 cites W2136294641 @default.
- W2000735805 cites W2137488327 @default.
- W2000735805 cites W2148220540 @default.
- W2000735805 cites W2148402694 @default.
- W2000735805 cites W2153859777 @default.
- W2000735805 cites W2163555597 @default.
- W2000735805 cites W2166109079 @default.
- W2000735805 cites W2312691728 @default.
- W2000735805 doi "https://doi.org/10.1177/0004563213511065" @default.
- W2000735805 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24197835" @default.
- W2000735805 hasPublicationYear "2013" @default.
- W2000735805 type Work @default.
- W2000735805 sameAs 2000735805 @default.
- W2000735805 citedByCount "10" @default.
- W2000735805 countsByYear W20007358052015 @default.
- W2000735805 countsByYear W20007358052017 @default.
- W2000735805 countsByYear W20007358052018 @default.
- W2000735805 countsByYear W20007358052019 @default.
- W2000735805 countsByYear W20007358052022 @default.
- W2000735805 crossrefType "journal-article" @default.
- W2000735805 hasAuthorship W2000735805A5062875328 @default.
- W2000735805 hasAuthorship W2000735805A5064917249 @default.
- W2000735805 hasAuthorship W2000735805A5067818460 @default.
- W2000735805 hasAuthorship W2000735805A5071112818 @default.
- W2000735805 hasAuthorship W2000735805A5077889482 @default.
- W2000735805 hasAuthorship W2000735805A5078189216 @default.
- W2000735805 hasConcept C126322002 @default.
- W2000735805 hasConcept C134018914 @default.
- W2000735805 hasConcept C203014093 @default.
- W2000735805 hasConcept C28328180 @default.
- W2000735805 hasConcept C500499127 @default.
- W2000735805 hasConcept C54355233 @default.
- W2000735805 hasConcept C553184892 @default.
- W2000735805 hasConcept C555293320 @default.
- W2000735805 hasConcept C71924100 @default.
- W2000735805 hasConcept C86803240 @default.
- W2000735805 hasConcept C90924648 @default.
- W2000735805 hasConceptScore W2000735805C126322002 @default.
- W2000735805 hasConceptScore W2000735805C134018914 @default.
- W2000735805 hasConceptScore W2000735805C203014093 @default.
- W2000735805 hasConceptScore W2000735805C28328180 @default.
- W2000735805 hasConceptScore W2000735805C500499127 @default.
- W2000735805 hasConceptScore W2000735805C54355233 @default.
- W2000735805 hasConceptScore W2000735805C553184892 @default.