FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000735982> ?p ?o ?g. }

• W2000735982 endingPage "465" @default.
• W2000735982 startingPage "457" @default.
• W2000735982 abstract "Summary The objective of this study was to assess protein levels for candidate cytokines, chemokines, growth factors, matrix metalloproteinases and their inhibitors in bronchoalveolar lavage fluid (BALF) in patients with polar forms of pulmonary sarcoidosis, i.e. Löfgren's syndrome (LS) and more advanced chest X-ray (CXR) stage III disease. Twenty-four inflammatory molecules were analysed in unconcentrated BALF samples from 10 sarcoidosis patients with CXR stage III and 10 patients with LS by semiquantitative protein array. Four novel molecules [CC chemokine ligand (CCL)15, CCL16, macrophage migration inhibitory factor (MIF) and macrophage stimulating protein (MSP)], detected for the first time in association with sarcoidosis, were then quantified by enzyme-linked immunosorbent assay in a second cohort of 68 sarcoidosis patients and 17 control subjects. The protein levels of CCL15, CCL16, CCL24, CXCL8, CXCL9, CXCL10, interleukin-16, MIF, MSP and matrix metallopeptidase 1 were increased in CXR stage III patients when compared with patients with LS. CCL15 and MSP up-regulation in CXR stage III patients in comparison with LS patients and controls was confirmed by enzyme-linked immunosorbent assay. Moreover, MSP was associated with treatment requirement (P = 0·001) and CCL15 was elevated in patients with disease progression at 2-year follow-up (P = 0·016). CCL16 levels were increased in sarcoidosis versus controls (P &lt; 0·05), but no difference was observed between patient subgroups. MIF up-regulation was not confirmed in a larger patient group. In conclusion, chemokines CCL15, CCL16 and MSP were found elevated for the first time in BALF from sarcoidosis patients; our results showed that CCL15 and MSP may affect disease course." @default.
• W2000735982 created "2016-06-24" @default.
• W2000735982 creator A5003945807 @default.
• W2000735982 creator A5016480427 @default.
• W2000735982 creator A5033599838 @default.
• W2000735982 creator A5035644782 @default.
• W2000735982 creator A5052114174 @default.
• W2000735982 creator A5074166442 @default.
• W2000735982 creator A5077461268 @default.
• W2000735982 creator A5077703779 @default.
• W2000735982 date "2009-01-07" @default.
• W2000735982 modified "2023-10-01" @default.
• W2000735982 title "Protein levels of CC chemokine ligand (CCL)15, CCL16 and macrophage stimulating protein in patients with sarcoidosis" @default.
• W2000735982 cites W1499068882 @default.
• W2000735982 cites W1581825270 @default.
• W2000735982 cites W1661041446 @default.
• W2000735982 cites W1860118976 @default.
• W2000735982 cites W1974783503 @default.
• W2000735982 cites W1977042335 @default.
• W2000735982 cites W1989180448 @default.
• W2000735982 cites W1994559611 @default.
• W2000735982 cites W2013285163 @default.
• W2000735982 cites W2018202283 @default.
• W2000735982 cites W2021348213 @default.
• W2000735982 cites W2023667966 @default.
• W2000735982 cites W2026841170 @default.
• W2000735982 cites W2029916671 @default.
• W2000735982 cites W2044565392 @default.
• W2000735982 cites W2049679215 @default.
• W2000735982 cites W2053910371 @default.
• W2000735982 cites W2055152614 @default.
• W2000735982 cites W2080106551 @default.
• W2000735982 cites W2082995652 @default.
• W2000735982 cites W2102227621 @default.
• W2000735982 cites W2106597066 @default.
• W2000735982 cites W2108573558 @default.
• W2000735982 cites W2115878608 @default.
• W2000735982 cites W2145495717 @default.
• W2000735982 cites W2152726130 @default.
• W2000735982 cites W2166860117 @default.
• W2000735982 cites W2338942075 @default.
• W2000735982 cites W4210977201 @default.
• W2000735982 cites W4210995779 @default.
• W2000735982 cites W4240206957 @default.
• W2000735982 doi "https://doi.org/10.1111/j.1365-2249.2008.03832.x" @default.
• W2000735982 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2669522" @default.
• W2000735982 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19220835" @default.
• W2000735982 hasPublicationYear "2009" @default.
• W2000735982 type Work @default.
• W2000735982 sameAs 2000735982 @default.
• W2000735982 citedByCount "22" @default.
• W2000735982 countsByYear W20007359822012 @default.
• W2000735982 countsByYear W20007359822014 @default.
• W2000735982 countsByYear W20007359822015 @default.
• W2000735982 countsByYear W20007359822016 @default.
• W2000735982 countsByYear W20007359822017 @default.
• W2000735982 countsByYear W20007359822018 @default.
• W2000735982 countsByYear W20007359822019 @default.
• W2000735982 countsByYear W20007359822020 @default.
• W2000735982 countsByYear W20007359822021 @default.
• W2000735982 crossrefType "journal-article" @default.
• W2000735982 hasAuthorship W2000735982A5003945807 @default.
• W2000735982 hasAuthorship W2000735982A5016480427 @default.
• W2000735982 hasAuthorship W2000735982A5033599838 @default.
• W2000735982 hasAuthorship W2000735982A5035644782 @default.
• W2000735982 hasAuthorship W2000735982A5052114174 @default.
• W2000735982 hasAuthorship W2000735982A5074166442 @default.
• W2000735982 hasAuthorship W2000735982A5077461268 @default.
• W2000735982 hasAuthorship W2000735982A5077703779 @default.
• W2000735982 hasBestOaLocation W20007359821 @default.
• W2000735982 hasConcept C104177226 @default.
• W2000735982 hasConcept C126322002 @default.
• W2000735982 hasConcept C13373296 @default.
• W2000735982 hasConcept C170217031 @default.
• W2000735982 hasConcept C17502307 @default.
• W2000735982 hasConcept C203014093 @default.
• W2000735982 hasConcept C2776914184 @default.
• W2000735982 hasConcept C2777714996 @default.
• W2000735982 hasConcept C2777961210 @default.
• W2000735982 hasConcept C2778690821 @default.
• W2000735982 hasConcept C2781301800 @default.
• W2000735982 hasConcept C5858377 @default.
• W2000735982 hasConcept C71924100 @default.
• W2000735982 hasConceptScore W2000735982C104177226 @default.
• W2000735982 hasConceptScore W2000735982C126322002 @default.
• W2000735982 hasConceptScore W2000735982C13373296 @default.
• W2000735982 hasConceptScore W2000735982C170217031 @default.
• W2000735982 hasConceptScore W2000735982C17502307 @default.
• W2000735982 hasConceptScore W2000735982C203014093 @default.
• W2000735982 hasConceptScore W2000735982C2776914184 @default.
• W2000735982 hasConceptScore W2000735982C2777714996 @default.
• W2000735982 hasConceptScore W2000735982C2777961210 @default.
• W2000735982 hasConceptScore W2000735982C2778690821 @default.
• W2000735982 hasConceptScore W2000735982C2781301800 @default.
• W2000735982 hasConceptScore W2000735982C5858377 @default.
• W2000735982 hasConceptScore W2000735982C71924100 @default.
• W2000735982 hasIssue "3" @default.
• W2000735982 hasLocation W20007359821 @default.

• next