Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000739166> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2000739166 abstract "<b>Introduction:</b> As it is always difficult to find the optimal combination of photosensitizer and of laser wavelength to achieve selective vascular damage in PWS-PDT, the selective vascular effects of HMME (Hematoporphyrin monomethyl ether) mediated PDT with 413 nm and with 532 nm were compared by mathematical simulation in this study. <b>Materials & Methods:</b> Firstly, distribution of 413 nm, 532 nm light in PWS tissue was simulated by Monte Carlo model. Two energy density groups were set, one is 80mW/cm<sup>2</sup>x40min for both 413 nm and 532 nm, the other is 80mW/cm<sup>2</sup>x40min for 532 nm while 80mW/cm<sup>2</sup>x20min in for 413 nm. Secondly, the productivity of reactive oxygen species (ROS) in target vessels and normal tissue were simulated using a simulation system for PDT of PWS established in our lab, which considering the amount of light and photosensitizer in tissue, the molar extinction coefficient of photosensitizer, and quantum yield of ROS. Concentration of HMME for each wavelength were same. Finally, the productivity of ROS n in target vessels and normal tissue were compared between 413 nm PDT and 532 nm PDT under different energy density. <b>Result:</b> Under the same energy density, ROS productivity in target vessels of 413 nm PDT was significantly higher than that of 532 nm PDT. Moreover, it was still higher at low energy density than that of 532nm PDT with high energy density. <b>Conclusion:</b> HMME mediated PDT using 413 nm has the potential to increase the selective vascular effect of PDT for PWS by shortening treatment time." @default.
- W2000739166 created "2016-06-24" @default.
- W2000739166 creator A5010641071 @default.
- W2000739166 creator A5034294435 @default.
- W2000739166 creator A5044864882 @default.
- W2000739166 creator A5048414136 @default.
- W2000739166 creator A5069772341 @default.
- W2000739166 creator A5079763060 @default.
- W2000739166 creator A5085207765 @default.
- W2000739166 date "2007-11-29" @default.
- W2000739166 modified "2023-09-23" @default.
- W2000739166 title "Comparison between HMME mediated photodynamic therapy using 413nm and 532nm for port wine stains: a mathematical simulation study" @default.
- W2000739166 doi "https://doi.org/10.1117/12.755783" @default.
- W2000739166 hasPublicationYear "2007" @default.
- W2000739166 type Work @default.
- W2000739166 sameAs 2000739166 @default.
- W2000739166 citedByCount "1" @default.
- W2000739166 crossrefType "proceedings-article" @default.
- W2000739166 hasAuthorship W2000739166A5010641071 @default.
- W2000739166 hasAuthorship W2000739166A5034294435 @default.
- W2000739166 hasAuthorship W2000739166A5044864882 @default.
- W2000739166 hasAuthorship W2000739166A5048414136 @default.
- W2000739166 hasAuthorship W2000739166A5069772341 @default.
- W2000739166 hasAuthorship W2000739166A5079763060 @default.
- W2000739166 hasAuthorship W2000739166A5085207765 @default.
- W2000739166 hasConcept C120665830 @default.
- W2000739166 hasConcept C121332964 @default.
- W2000739166 hasConcept C178790620 @default.
- W2000739166 hasConcept C185592680 @default.
- W2000739166 hasConcept C192562407 @default.
- W2000739166 hasConcept C2780699678 @default.
- W2000739166 hasConcept C2781323092 @default.
- W2000739166 hasConcept C2781469039 @default.
- W2000739166 hasConcept C49040817 @default.
- W2000739166 hasConcept C520434653 @default.
- W2000739166 hasConcept C6260449 @default.
- W2000739166 hasConcept C75473681 @default.
- W2000739166 hasConcept C76046532 @default.
- W2000739166 hasConceptScore W2000739166C120665830 @default.
- W2000739166 hasConceptScore W2000739166C121332964 @default.
- W2000739166 hasConceptScore W2000739166C178790620 @default.
- W2000739166 hasConceptScore W2000739166C185592680 @default.
- W2000739166 hasConceptScore W2000739166C192562407 @default.
- W2000739166 hasConceptScore W2000739166C2780699678 @default.
- W2000739166 hasConceptScore W2000739166C2781323092 @default.
- W2000739166 hasConceptScore W2000739166C2781469039 @default.
- W2000739166 hasConceptScore W2000739166C49040817 @default.
- W2000739166 hasConceptScore W2000739166C520434653 @default.
- W2000739166 hasConceptScore W2000739166C6260449 @default.
- W2000739166 hasConceptScore W2000739166C75473681 @default.
- W2000739166 hasConceptScore W2000739166C76046532 @default.
- W2000739166 hasLocation W20007391661 @default.
- W2000739166 hasOpenAccess W2000739166 @default.
- W2000739166 hasPrimaryLocation W20007391661 @default.
- W2000739166 hasRelatedWork W2000739166 @default.
- W2000739166 hasRelatedWork W2002972226 @default.
- W2000739166 hasRelatedWork W2065486124 @default.
- W2000739166 hasRelatedWork W2096677437 @default.
- W2000739166 hasRelatedWork W2290863662 @default.
- W2000739166 hasRelatedWork W2325628170 @default.
- W2000739166 hasRelatedWork W2361826106 @default.
- W2000739166 hasRelatedWork W2414778858 @default.
- W2000739166 hasRelatedWork W2437441552 @default.
- W2000739166 hasRelatedWork W3024900980 @default.
- W2000739166 isParatext "false" @default.
- W2000739166 isRetracted "false" @default.
- W2000739166 magId "2000739166" @default.
- W2000739166 workType "article" @default.