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- W2000744001 abstract "A parameter of peripheral insulin activity (A = 10(4)/IpGp) can be obtained after oral glucose loading by simple calcuation using insulin and glucose levels at the glucose peak. In combination with a glucose-independent parameter of beta-cell function (CIR = 100· I/G(G-70) a parameter of glucose tolerance (GT = A · CIR) is defined. The parameters allow one to separate the contributions of beta-cell function and peripheral insulin resistance to the glucose tolerance observed after glucose loading. Examples, based on the literature and our own work, illustrate the increase of A and GT by cortisone acetate premedication as well as long-term oral contraceptive medication." @default.
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- W2000744001 date "1976-04-01" @default.
- W2000744001 modified "2023-09-23" @default.
- W2000744001 title "Glucose Tolerance and Insulin Release, A Mathematical Approach: II. Approximation of the Peripheral Insulin Resistance After Oral Glucose Loading" @default.
- W2000744001 doi "https://doi.org/10.2337/diab.25.4.245" @default.
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