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- W2000744598 abstract "Atherosclerosis-induced coronary heart disease remains the major cause of death and disability in industrialized countries. Hypercholesterolemia is recognized as a causative factor in the development of atherosclerosis. While the lowering of cholesterol levels as a treatment goal has met with general agreement and acceptance, the preferred methods for doing so are still open to conjecture. This literature review discusses various factors in the hypercho-lesierolemia-atherosclerosis link and surveys a variety of treatment protocols including diet modification, drug therapy, surgical intervention, and plasmapheresis. Evidence is accumulating to prove that the ideal hypercholes-terolemia therapy is one that reduces LDL levels while maintaining or increasing HDL levels. Because LDL-apheresis has this potential, this paper also reviews the various LDL-apheresis methods, including immunoadsorp-tion, chemical affinity,' and double-membrane filtration." @default.
- W2000744598 created "2016-06-24" @default.
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- W2000744598 date "1988-01-01" @default.
- W2000744598 modified "2023-09-27" @default.
- W2000744598 title "Hypercholesterolemia and atherosclerosis: Present and future therapy including LDL-apheresis" @default.
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- W2000744598 doi "https://doi.org/10.1002/jca.2920040108" @default.
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