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- W2000746171 abstract "The cytoplasmic pH undergoes a biphasic change when neutrophils are activated. The role of Ca2+ in initiating these changes was investigated. No correlation was found between the increased cytosolic [Ca2+] and the stimulation of the Na+/H+ antiport. Similarly, the cytoplasmic acidification elicited by activation in Na+-free media was found to be unrelated to [Ca2+]. Reversal of Na+/H+ exchange was also ruled out as the source of the acidification. Data using a variety of soluble activators indicate that metabolic acid generation is largely responsible for the observed drop in cytoplasmic pH." @default.
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- W2000746171 date "1988-02-01" @default.
- W2000746171 modified "2023-09-27" @default.
- W2000746171 title "Cytosolic calcium, oxygen consumption and the intracellular pH of stimulated neutrophils" @default.
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- W2000746171 doi "https://doi.org/10.1007/bf01128973" @default.
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