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- W2000748844 abstract "Fulfillment of the promise of the genomic revolution for personalizing cancer therapy will depend on the ability to identify specific alterations in tumor cells that are critical to their growth, and the development of drugs that can target these alterations and inhibit their growth. In this report, examples of where this has been successful are discussed, and the challenges faced in other cases are described. The identification of the patients most likely to benefit from targeted agents requires significant investment in the development and validation of predictive assays. The Program for the Assessment of Clinical Cancer Tests (PACCT) has proposed an approach that should speed the development of the diagnostic tools required and their acceptance into clinical practice. This approach is dependent on determining the most pressing clinical questions confronting clinicians today and the availability of adequate specimens to validate the assays." @default.
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- W2000748844 date "2005-11-01" @default.
- W2000748844 modified "2023-09-24" @default.
- W2000748844 title "Program for the Assessment of Clinical Cancer Tests (PACCT): assisting the development of tailored cancer therapy" @default.
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- W2000748844 doi "https://doi.org/10.2217/17410541.2.4.363" @default.
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