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- W2000755117 abstract "The relationship between the histocompatibility leukocyte antigen (HLA) phenotypes and the clinical course of myasthenia gravis (MG) was studied in 53 Japanese patients with MG. The frequency of HLA-DRw9 antigen was high in the MG patients who did not need immunosuppressive therapy but only anticholinesterase agents (RR = 4.52; CP < 0.02), who achieved remission of the disease (RR = 2.98; CP < 0.05) or two showed a decrease in AChR antibody (Ab) titer (RR = 6.32; CP < 0.0002) whereas the frequency of HLA-DRw8 antigen was increased in MG patients who underwent immunosuppressive therapy (RR = 4.03; CP < 0.01), who did not have remission (RR = 4.75; CP < 0.1) or who showed an increase in AChR Ab titer (RR = 6.48; CP < 0.01). These data suggest that immunogenetic heterogeneity in MG might be reflected in its clinical course." @default.
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- W2000755117 date "1988-05-01" @default.
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- W2000755117 title "Involvement of HLA in clinical courses of myasthenia gravis" @default.
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- W2000755117 doi "https://doi.org/10.1016/0165-5728(88)90064-1" @default.
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