Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000759914> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2000759914 endingPage "87" @default.
- W2000759914 startingPage "83" @default.
- W2000759914 abstract "Cathechol-O-methyltransferase (COMT) regulates the amount of dopamine in the prefrontal cortex (PFC). Substantial studies indicate a close relationship between COMT and several human psychotic disorders. The case–control method was used to study the association between mental retardation (MR) and genetic variants of COMT. Three single nucleotide polymorphisms (SNPs: rs4680, rs165656 and rs165774), in the cathechol-O-methyltransferase (COMT) gene, were genotyped by PCR–RFLP method. Individual SNP analysis shows significant differences only at SNP rs165656 for both genotype and allele frequency when comparing MR cases and controls (p = 0.023, 0.011, respectively). Further haplotype analysis indicates that there are two haplotype sets, rs165656–rs4680 and rs165656–rs165774, which show statistical differences between MR cases and controls (global p = 0.047, p = 0.033, respectively). Our results suggest a positive association between the genetic variants of the COMT gene and MR in the Chinese Han population in the Qinba region." @default.
- W2000759914 created "2016-06-24" @default.
- W2000759914 creator A5002883158 @default.
- W2000759914 creator A5014939323 @default.
- W2000759914 creator A5020916618 @default.
- W2000759914 creator A5033419531 @default.
- W2000759914 creator A5038883907 @default.
- W2000759914 creator A5046581897 @default.
- W2000759914 creator A5050745363 @default.
- W2000759914 creator A5069915515 @default.
- W2000759914 date "2007-05-01" @default.
- W2000759914 modified "2023-09-25" @default.
- W2000759914 title "An association study between cathechol-O-methyltransferase gene and mental retardation in the Chinese Han population" @default.
- W2000759914 cites W1584047372 @default.
- W2000759914 cites W1659384861 @default.
- W2000759914 cites W1996395058 @default.
- W2000759914 cites W2006373408 @default.
- W2000759914 cites W2015098351 @default.
- W2000759914 cites W2017930968 @default.
- W2000759914 cites W2044431079 @default.
- W2000759914 cites W2050074375 @default.
- W2000759914 cites W2054856852 @default.
- W2000759914 cites W2068306689 @default.
- W2000759914 cites W2069863414 @default.
- W2000759914 cites W2071670996 @default.
- W2000759914 cites W2086286256 @default.
- W2000759914 cites W2104532643 @default.
- W2000759914 cites W2110755408 @default.
- W2000759914 cites W2135835694 @default.
- W2000759914 cites W2138222426 @default.
- W2000759914 cites W2318367847 @default.
- W2000759914 doi "https://doi.org/10.1016/j.neulet.2007.03.050" @default.
- W2000759914 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17442488" @default.
- W2000759914 hasPublicationYear "2007" @default.
- W2000759914 type Work @default.
- W2000759914 sameAs 2000759914 @default.
- W2000759914 citedByCount "11" @default.
- W2000759914 countsByYear W20007599142012 @default.
- W2000759914 countsByYear W20007599142017 @default.
- W2000759914 countsByYear W20007599142018 @default.
- W2000759914 countsByYear W20007599142020 @default.
- W2000759914 crossrefType "journal-article" @default.
- W2000759914 hasAuthorship W2000759914A5002883158 @default.
- W2000759914 hasAuthorship W2000759914A5014939323 @default.
- W2000759914 hasAuthorship W2000759914A5020916618 @default.
- W2000759914 hasAuthorship W2000759914A5033419531 @default.
- W2000759914 hasAuthorship W2000759914A5038883907 @default.
- W2000759914 hasAuthorship W2000759914A5046581897 @default.
- W2000759914 hasAuthorship W2000759914A5050745363 @default.
- W2000759914 hasAuthorship W2000759914A5069915515 @default.
- W2000759914 hasConcept C104317684 @default.
- W2000759914 hasConcept C135763542 @default.
- W2000759914 hasConcept C139275648 @default.
- W2000759914 hasConcept C153209595 @default.
- W2000759914 hasConcept C180754005 @default.
- W2000759914 hasConcept C185361966 @default.
- W2000759914 hasConcept C186413461 @default.
- W2000759914 hasConcept C197754878 @default.
- W2000759914 hasConcept C2778524067 @default.
- W2000759914 hasConcept C2908647359 @default.
- W2000759914 hasConcept C54355233 @default.
- W2000759914 hasConcept C71924100 @default.
- W2000759914 hasConcept C86803240 @default.
- W2000759914 hasConcept C99454951 @default.
- W2000759914 hasConceptScore W2000759914C104317684 @default.
- W2000759914 hasConceptScore W2000759914C135763542 @default.
- W2000759914 hasConceptScore W2000759914C139275648 @default.
- W2000759914 hasConceptScore W2000759914C153209595 @default.
- W2000759914 hasConceptScore W2000759914C180754005 @default.
- W2000759914 hasConceptScore W2000759914C185361966 @default.
- W2000759914 hasConceptScore W2000759914C186413461 @default.
- W2000759914 hasConceptScore W2000759914C197754878 @default.
- W2000759914 hasConceptScore W2000759914C2778524067 @default.
- W2000759914 hasConceptScore W2000759914C2908647359 @default.
- W2000759914 hasConceptScore W2000759914C54355233 @default.
- W2000759914 hasConceptScore W2000759914C71924100 @default.
- W2000759914 hasConceptScore W2000759914C86803240 @default.
- W2000759914 hasConceptScore W2000759914C99454951 @default.
- W2000759914 hasIssue "1" @default.
- W2000759914 hasLocation W20007599141 @default.
- W2000759914 hasLocation W20007599142 @default.
- W2000759914 hasOpenAccess W2000759914 @default.
- W2000759914 hasPrimaryLocation W20007599141 @default.
- W2000759914 hasRelatedWork W1598350073 @default.
- W2000759914 hasRelatedWork W2000759914 @default.
- W2000759914 hasRelatedWork W2004289955 @default.
- W2000759914 hasRelatedWork W2011358557 @default.
- W2000759914 hasRelatedWork W2050074375 @default.
- W2000759914 hasRelatedWork W2135389814 @default.
- W2000759914 hasRelatedWork W2339961551 @default.
- W2000759914 hasRelatedWork W2360977025 @default.
- W2000759914 hasRelatedWork W2408752853 @default.
- W2000759914 hasRelatedWork W3173233857 @default.
- W2000759914 hasVolume "419" @default.
- W2000759914 isParatext "false" @default.
- W2000759914 isRetracted "false" @default.
- W2000759914 magId "2000759914" @default.
- W2000759914 workType "article" @default.