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- W2000761693 abstract "A new, efficient synthesis of sphingofungin F has been accomplished with 10.4% overall yield in 15 steps. The salient features of the synthesis are the utilization of methyl tricyclic iminolactone 3 for the asymmetric aldol reaction as a key step to introduce two desired stereogenic centers, one-pot reaction for the synthesis of ω-hydroxyketone from ε-caprolactone, and an effective one-step deprotection strategy to remove all protecting groups using 0.2 N HCl." @default.
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- W2000761693 date "2010-03-23" @default.
- W2000761693 modified "2023-09-27" @default.
- W2000761693 title "Total Synthesis of Sphingofungin F Based on Chiral Tricyclic Iminolactone" @default.
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- W2000761693 doi "https://doi.org/10.1021/jo100183d" @default.
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