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• W2000766818 abstract "We compared 11 patients with upper airway obstruction (obstruction at or proximal to the carina) to 22 patients with chronic obstructive pulmonary disease and to 15 normal subjects utilizing spirometry, lung volumes, airway resistance, maximal voluntary ventilation, single-breath diffusion capacity, and maximal inspiratory and expiratory flow-volume loops. Four values usually distinguished patients with upper airway obstruction: (1) forced inspiratory flow at 50 percent of the vital capacity (FIF50%) ≤ 100 L/min; (2) ratio of forced expiratory flow at 50 percent of the vital capacity to the FIF50% (FEF50%/FIF50%) ≥ 1; (3) ratio of the forced expiratory volume in one second measured in milliliters to the peak expiratory flow rate in liters per minute (FEV1/ PEFR) ≥ 10 ml/L/min; and (4) ratio of the forced expired volume in one second to the forced expired volume in 0.5 second (FEV1/FEV0.5) ≥ 1.5. The last ratio can be determined with a simple spirometer. We compared 11 patients with upper airway obstruction (obstruction at or proximal to the carina) to 22 patients with chronic obstructive pulmonary disease and to 15 normal subjects utilizing spirometry, lung volumes, airway resistance, maximal voluntary ventilation, single-breath diffusion capacity, and maximal inspiratory and expiratory flow-volume loops. Four values usually distinguished patients with upper airway obstruction: (1) forced inspiratory flow at 50 percent of the vital capacity (FIF50%) ≤ 100 L/min; (2) ratio of forced expiratory flow at 50 percent of the vital capacity to the FIF50% (FEF50%/FIF50%) ≥ 1; (3) ratio of the forced expiratory volume in one second measured in milliliters to the peak expiratory flow rate in liters per minute (FEV1/ PEFR) ≥ 10 ml/L/min; and (4) ratio of the forced expired volume in one second to the forced expired volume in 0.5 second (FEV1/FEV0.5) ≥ 1.5. The last ratio can be determined with a simple spirometer." @default.
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• W2000766818 date "1975-12-01" @default.
• W2000766818 modified "2023-10-15" @default.
• W2000766818 title "Diagnosis of Upper Airway Obstruction by Pulmonary Function Testing" @default.
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• W2000766818 doi "https://doi.org/10.1378/chest.68.6.796" @default.
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