FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000767788> ?p ?o ?g. }

• W2000767788 endingPage "865" @default.
• W2000767788 startingPage "859" @default.
• W2000767788 abstract "Patients with clinical Stage I and II Hodgkin's disease have been managed at the Princess Margaret Hospital for over 20 years, without the use of routine staging laparotomy. Our experience identified as adverse prognostic factors presence of a large mediastinal mass, B symptoms, and advanced age in presence of unfavorable histology (20). We had suggested previously that the use of extended field radiation therapy (XRT) was associated with a lower risk of relapse than involved field XRT or mantle XRT. There has been a trend over the past decade to select those patients with favorable prognostic factors for treatment with XRT alone and to use mantle plus upper abdominal XRT (extended field XRT) to treat them. A retrospective study of patients with clinical Stage I and II Hodgkin's disease treated at the Princess Margaret Hospital between 1978 and 1986 was conducted to determine the impact of patient selection and extended field radiation on outcome. The study involved 250 patients with supradiaphragmatic disease selected for treatment with radiation alone on the absence of adverse prognostic factors. Radiation techniques included involved field radiation in selected patients (those with upper neck involvement), mantle radiation in the earlier years, and mantle plus upper abdominal radiation in the later years of the study. Actuarial survival was 83.3% at 8 years; cause-specific survival was 90.1% and the relapse-free rate 71.6%. Local tumor control was 94.6%; only two patients had true infield failure. Multivariate analysis showed that significant prognostic factors included age, histology, and erythrocyte sedimentation rate. Extent of the radiation treatment volume was significant and influenced the risk of relapse, particularly out-of-field relapse, independently of other factors. A dose of 35 Gy was found to be sufficient for control of clinical disease. This study validated a previously developed model for the selection of clinically staged patients with Stage I and II Hodgkin's disease for treatment with radiation alone. Careful selection of these patients can yield excellent results without requiring that staging laparotomy be routinely performed or the use of systemic chemotherapy as the initial treatment." @default.
• W2000767788 created "2016-06-24" @default.
• W2000767788 creator A5011183388 @default.
• W2000767788 creator A5014347189 @default.
• W2000767788 creator A5015664246 @default.
• W2000767788 creator A5033352311 @default.
• W2000767788 creator A5046078075 @default.
• W2000767788 creator A5055681005 @default.
• W2000767788 creator A5061721154 @default.
• W2000767788 creator A5067372361 @default.
• W2000767788 creator A5068437938 @default.
• W2000767788 creator A5071261633 @default.
• W2000767788 creator A5075569426 @default.
• W2000767788 date "1992-01-01" @default.
• W2000767788 modified "2023-09-27" @default.
• W2000767788 title "Analysis of supradiaphragmatic clinical stage I and II Hodgkin's disease treated with radiation alone" @default.
• W2000767788 cites W108277866 @default.
• W2000767788 cites W1829707378 @default.
• W2000767788 cites W1982346408 @default.
• W2000767788 cites W1999254196 @default.
• W2000767788 cites W2012127560 @default.
• W2000767788 cites W2019085302 @default.
• W2000767788 cites W2034657211 @default.
• W2000767788 cites W2038252730 @default.
• W2000767788 cites W2040018761 @default.
• W2000767788 cites W2051767052 @default.
• W2000767788 cites W2085140160 @default.
• W2000767788 cites W2092248185 @default.
• W2000767788 cites W2131969355 @default.
• W2000767788 cites W2143594378 @default.
• W2000767788 cites W2248977291 @default.
• W2000767788 cites W2262020339 @default.
• W2000767788 cites W2262106173 @default.
• W2000767788 cites W2322312023 @default.
• W2000767788 doi "https://doi.org/10.1016/0360-3016(92)90780-l" @default.
• W2000767788 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1555977" @default.
• W2000767788 hasPublicationYear "1992" @default.
• W2000767788 type Work @default.
• W2000767788 sameAs 2000767788 @default.
• W2000767788 citedByCount "72" @default.
• W2000767788 countsByYear W20007677882012 @default.
• W2000767788 countsByYear W20007677882014 @default.
• W2000767788 countsByYear W20007677882017 @default.
• W2000767788 countsByYear W20007677882020 @default.
• W2000767788 crossrefType "journal-article" @default.
• W2000767788 hasAuthorship W2000767788A5011183388 @default.
• W2000767788 hasAuthorship W2000767788A5014347189 @default.
• W2000767788 hasAuthorship W2000767788A5015664246 @default.
• W2000767788 hasAuthorship W2000767788A5033352311 @default.
• W2000767788 hasAuthorship W2000767788A5046078075 @default.
• W2000767788 hasAuthorship W2000767788A5055681005 @default.
• W2000767788 hasAuthorship W2000767788A5061721154 @default.
• W2000767788 hasAuthorship W2000767788A5067372361 @default.
• W2000767788 hasAuthorship W2000767788A5068437938 @default.
• W2000767788 hasAuthorship W2000767788A5071261633 @default.
• W2000767788 hasAuthorship W2000767788A5075569426 @default.
• W2000767788 hasConcept C126322002 @default.
• W2000767788 hasConcept C141071460 @default.
• W2000767788 hasConcept C146357865 @default.
• W2000767788 hasConcept C151730666 @default.
• W2000767788 hasConcept C167135981 @default.
• W2000767788 hasConcept C2779134260 @default.
• W2000767788 hasConcept C509974204 @default.
• W2000767788 hasConcept C71924100 @default.
• W2000767788 hasConcept C86803240 @default.
• W2000767788 hasConceptScore W2000767788C126322002 @default.
• W2000767788 hasConceptScore W2000767788C141071460 @default.
• W2000767788 hasConceptScore W2000767788C146357865 @default.
• W2000767788 hasConceptScore W2000767788C151730666 @default.
• W2000767788 hasConceptScore W2000767788C167135981 @default.
• W2000767788 hasConceptScore W2000767788C2779134260 @default.
• W2000767788 hasConceptScore W2000767788C509974204 @default.
• W2000767788 hasConceptScore W2000767788C71924100 @default.
• W2000767788 hasConceptScore W2000767788C86803240 @default.
• W2000767788 hasIssue "5" @default.
• W2000767788 hasLocation W20007677881 @default.
• W2000767788 hasLocation W20007677882 @default.
• W2000767788 hasOpenAccess W2000767788 @default.
• W2000767788 hasPrimaryLocation W20007677881 @default.
• W2000767788 hasRelatedWork W1586374228 @default.
• W2000767788 hasRelatedWork W2003938723 @default.
• W2000767788 hasRelatedWork W2047967234 @default.
• W2000767788 hasRelatedWork W2118496982 @default.
• W2000767788 hasRelatedWork W2364998975 @default.
• W2000767788 hasRelatedWork W2369162477 @default.
• W2000767788 hasRelatedWork W2439875401 @default.
• W2000767788 hasRelatedWork W4220939315 @default.
• W2000767788 hasRelatedWork W4238867864 @default.
• W2000767788 hasRelatedWork W2525756941 @default.
• W2000767788 hasVolume "22" @default.
• W2000767788 isParatext "false" @default.
• W2000767788 isRetracted "false" @default.
• W2000767788 magId "2000767788" @default.
• W2000767788 workType "article" @default.