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• W2000774921 abstract "Dry age-related macular degeneration (AMD), also called geographic atrophy, is characterized by the atrophy of outer retinal layers and retinal pigment epithelium (RPE) cells. Dry AMD accounts for 80% of all intermediate and advanced forms of the disease. Although vision loss is mainly due to the neovascular form (75%), dry AMD remains a challenge for ophthalmologists because of the lack of effective therapies. Actual management consists of lifestyle modification, vitamin supplements, and supportive measures in the advanced stages. The Age-Related Eye Disease Study demonstrated a statistically significant protective effect of dietary supplementation of antioxidants (vitamin C, vitamin E, beta-carotene, zinc, and copper) on dry AMD progression rate. It was also stated that the consumption of omega-3 polyunsaturated fatty acids, such as docosahexaenoic acid and eicosapentaenoic acid, has protective effects. Other antioxidants, vitamins, and minerals (such as crocetin, curcumin, and vitamins B9, B12, and B6) are under evaluation, but the results are still uncertain. New strategies aim to 1) reduce or block drusen formation, 2) reduce or eliminate inflammation, 3) lower the accumulation of toxic by-products from the visual cycle, 4) reduce or eliminate retinal oxidative stress, 5) improve choroidal perfusion, 6) replace/repair or regenerate lost RPE cells and photoreceptors with stem cell therapy, and 7) develop a target gene therapy." @default.
• W2000774921 created "2016-06-24" @default.
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• W2000774921 date "2015-04-01" @default.
• W2000774921 modified "2023-09-30" @default.
• W2000774921 title "Recent developments in the management of dry age-related macular degeneration" @default.
• W2000774921 cites W1483046663 @default.
• W2000774921 cites W1506449639 @default.
• W2000774921 cites W1540386079 @default.
• W2000774921 cites W158938192 @default.
• W2000774921 cites W1793293664 @default.
• W2000774921 cites W1822386544 @default.
• W2000774921 cites W1883306593 @default.
• W2000774921 cites W194760794 @default.
• W2000774921 cites W1966846271 @default.
• W2000774921 cites W1968779486 @default.
• W2000774921 cites W1970166652 @default.
• W2000774921 cites W1970714860 @default.
• W2000774921 cites W1971273556 @default.
• W2000774921 cites W1972955056 @default.
• W2000774921 cites W1974943838 @default.
• W2000774921 cites W1978438207 @default.
• W2000774921 cites W1978753457 @default.
• W2000774921 cites W1980954887 @default.
• W2000774921 cites W1983877288 @default.
• W2000774921 cites W1986531295 @default.
• W2000774921 cites W1988549472 @default.
• W2000774921 cites W1989747234 @default.
• W2000774921 cites W1990300173 @default.
• W2000774921 cites W1996024251 @default.
• W2000774921 cites W1996938622 @default.
• W2000774921 cites W1999383714 @default.
• W2000774921 cites W2003101845 @default.
• W2000774921 cites W2010977640 @default.
• W2000774921 cites W2012666350 @default.
• W2000774921 cites W2013737946 @default.
• W2000774921 cites W2017083562 @default.
• W2000774921 cites W2017897136 @default.
• W2000774921 cites W2018935876 @default.
• W2000774921 cites W2024116613 @default.
• W2000774921 cites W2025313923 @default.
• W2000774921 cites W2028701630 @default.
• W2000774921 cites W2031564141 @default.
• W2000774921 cites W2048051759 @default.
• W2000774921 cites W2049022098 @default.
• W2000774921 cites W2049825753 @default.
• W2000774921 cites W2062407374 @default.
• W2000774921 cites W2066326071 @default.
• W2000774921 cites W2070628315 @default.
• W2000774921 cites W2074165817 @default.
• W2000774921 cites W2074276049 @default.
• W2000774921 cites W2077366389 @default.
• W2000774921 cites W2078350394 @default.
• W2000774921 cites W2082032407 @default.
• W2000774921 cites W2083242977 @default.
• W2000774921 cites W2088306477 @default.
• W2000774921 cites W2088551743 @default.
• W2000774921 cites W2088866871 @default.
• W2000774921 cites W2089944736 @default.
• W2000774921 cites W2092638574 @default.
• W2000774921 cites W2092816889 @default.
• W2000774921 cites W2096543412 @default.
• W2000774921 cites W2101829150 @default.
• W2000774921 cites W2103161598 @default.
• W2000774921 cites W2109130048 @default.
• W2000774921 cites W2115932454 @default.
• W2000774921 cites W2116794040 @default.
• W2000774921 cites W2117906875 @default.
• W2000774921 cites W2117917811 @default.
• W2000774921 cites W2122311980 @default.
• W2000774921 cites W2127688669 @default.
• W2000774921 cites W2128803651 @default.
• W2000774921 cites W2128887692 @default.
• W2000774921 cites W2129572698 @default.
• W2000774921 cites W2135957358 @default.
• W2000774921 cites W2142329900 @default.
• W2000774921 cites W2144469043 @default.
• W2000774921 cites W2147904592 @default.
• W2000774921 cites W2149062776 @default.
• W2000774921 cites W2149925846 @default.
• W2000774921 cites W2155236757 @default.
• W2000774921 cites W2168912282 @default.
• W2000774921 cites W2172232070 @default.
• W2000774921 cites W2419255724 @default.
• W2000774921 cites W2598520882 @default.
• W2000774921 cites W4230439113 @default.
• W2000774921 cites W62535517 @default.
• W2000774921 cites W90671621 @default.
• W2000774921 cites W95909858 @default.
• W2000774921 doi "https://doi.org/10.2147/opth.s59724" @default.
• W2000774921 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4388086" @default.
• W2000774921 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25878491" @default.

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