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- W2000776461 abstract "Obesity is associated to a delayed wound healing and prolonged inflammatory phase. Laser light has shown positiveresults in the photobiomodulation of tissue repair; however, its use associated with systemic disorders such as obesity isstill little explored in the literature. The aim of this study was to validate an experimental system for studying weightgaining by consuming a high fat called cafeteria diet (CD) for the induction of obesity. Forty-eight rats wereweaned, divided into two experimental groups: standard (SD) and Cafeteria Diet (CD). Free feeding was carried outduring 20 weeks and the mass gaining was accompanied. After general anesthesia standardized surgical wounds werecreated (1cm 2 ) in the dorsal midline region of each animal. Both groups (SD; CD) were divided into 2 subgroups of 12 animals, G1 and G3 (non-irradiated) and G2 and G4 (irradiated). The irradiation protocols (λ660 nm, 40 mW, CW; 24J/cm2) started immediately after surgery and were repeated every other day during 14 days. The rats were killed at the8th or 15th days after surgery. The abdominal fat was removed and weighed to verify the success of the inductiontechnique. The specimens were taken and routinely processed histology (hematoxylin/eosin) was performed. It wasconcluded that the ingestion of fast-food increased abdominal fat in rats and modified the inflammatory pattern of thehealing. Laser phototherapy in the parameters employed decreased inflammatory intensity quickening wound healing inobese rats." @default.
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- W2000776461 date "2014-02-18" @default.
- W2000776461 modified "2023-09-23" @default.
- W2000776461 title "Laser photobiomodulation as an adjunct of the wound healing impairment of rats exposed to a cafeteria diet" @default.
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- W2000776461 doi "https://doi.org/10.1117/12.2040807" @default.
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