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- W2000779520 abstract "In the 40 years after the first description of sickle cell disease in 1910, roughly a paper per decade described neurologic complications, including stroke, and attributed them to the likes of anemia, fever, meningitis, hemorrhage, and even cerebral fat embolism. Improvements in the diagnosis of sickle cell anemia allowed larger cohorts to be studied, and new techniques of brain imaging, first CT scans1 and then magnetic resonance imaging,2 , 3 have amply confirmed that stroke is a major problem in sickle cell disease, with a prevalence ranging from 5.5 percent1 to 17 percent.4 Infarction occurs mainly in younger patients, and hemorrhage in . . ." @default.
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- W2000779520 date "1992-02-27" @default.
- W2000779520 modified "2023-10-17" @default.
- W2000779520 title "Sickle Cell Anemia, Stroke, and Transcranial Doppler Studies" @default.
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- W2000779520 doi "https://doi.org/10.1056/nejm199202273260911" @default.
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