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• W2000781129 abstract "Human chorionic gonadotropin, hCG, a hormone which increases intracellular cAMP, provoked rapid (30 s) and sustained (up to 30 min) increases in the levels of inositol mono-, bis- and trisphosphates (IP, IP2 and IP3, respectively) in bovine luteal cells. LiCl (10 mM) enhanced inositol phosphate accumulation in response to hCG. Concentration-dependent increases in inositol phosphates, cAMP and progesterone accumulation were observed in hCG-treated luteal cells. hCG also induced rapid and concentration-dependent increases in cytosolic free Ca2+ as measured by quin 2 fluorescence. These findings demonstrate that hCG stimulates the phospholipase C-IP3 and diacylglycerol 'second messenger' system in the bovine corpus luteum." @default.
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• W2000781129 date "1986-11-24" @default.
• W2000781129 modified "2023-09-26" @default.
• W2000781129 title "Human chorionic gonadotropin activates the inositol 1,4,5-trisphosphate-Ca²⁺intracellular signalling system in bovine luteal cells" @default.
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• W2000781129 doi "https://doi.org/10.1016/0014-5793(86)81034-1" @default.
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