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- W2000782379 abstract "Mycobacterium bovis BCG and its subcellular components (bacterial extract, culture filtrate, purified protein derivative, and muramyl dipeptide MDP) are potent in vitro IL-6 inducers in spleen cell cultures from uninfected and BCG-infected BALB/c mice. Both plastic adherent and nonadherent spleen cells are capable of producing IL-6. Athymic nude mice produce more IL-6 than euthymic mice, suggesting that monocyte/macrophages are the main IL-6-producing cells in response to BCG. Finally, IL-6 production seems to be controlled to some extent by T lymphocytes, as down-regulation of CD4+ cells resulted in a marked increase in IL-6 production. Interferon-γ does not seem to be involved in this regulation." @default.
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- W2000782379 date "1991-10-01" @default.
- W2000782379 modified "2023-09-30" @default.
- W2000782379 title "Interleukin-6 production in Mycobacterium bovis BCG-infected mice" @default.
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- W2000782379 doi "https://doi.org/10.1016/0008-8749(91)90071-i" @default.
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