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• W2000783655 abstract "A primary concern of any multihospital clinical trial is the recruitment of a predetermined number of patients during a prespecified interval of time. In several recent papers a Poisson based model was used to estimate the time needed to recruit a predetermined number of patients and the probabilities of recruiting specified fractions of the sample during subintervals. The Poisson model requires the assumption that patients be recruited at a constant rate over the entire length of the interval. In this paper we test the adequacy of this model and assumption using patient intake data from nine multihospital VA clinical trials and propose an alternative Bayesian model." @default.
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• W2000783655 date "1987-01-01" @default.
• W2000783655 modified "2023-09-25" @default.
• W2000783655 title "The “constant intake rate” assumption in interim recruitment goal methodology for multicenter clinical trials" @default.
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• W2000783655 doi "https://doi.org/10.1016/0021-9681(87)90045-2" @default.
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