FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000784227> ?p ?o ?g. }

• W2000784227 endingPage "285" @default.
• W2000784227 startingPage "275" @default.
• W2000784227 abstract "The Gram-negative bacterium Rhizobium meliloti contains two distinct malic enzymes. We report the purification of the two isozymes to homogeneity, and their in vitro characterization. Both enzymes exhibit unusually high subunit molecular weights of about 82 kDa. The NAD(P)+ specific malic enzyme [EC 1.1.1.39] exhibits positive co-operativity with respect to malate, but Michaelis-Menten type behavior with respect to the co-factors NAD+ or NADP+. The enzyme is subject to substrate inhibition, and shows allosteric regulation by acetyl-CoA, an effect that has so far only been described for some NADP+ dependent malic enzymes. Its activity is positively regulated by succinate and fumarate. In contrast to the NAD(P)+ specific malic enzyme, the NADP+ dependent malic enzyme [EC 1.1.1.40] shows Michaelis-Menten type behavior with respect to malate and NADP+. Apart from product inhibition, the enzyme is not subjected to any regulatory mechanism. Neither reductive carboxylation of pyruvate, nor decarboxylation of oxaloacetate, could be detected for either malic enzyme. Our characterization of the two R. meliloti malic enzymes therefore suggests a number of features uncharacteristic for malic enzymes described so far." @default.
• W2000784227 created "2016-06-24" @default.
• W2000784227 creator A5000015314 @default.
• W2000784227 creator A5031720116 @default.
• W2000784227 creator A5091657224 @default.
• W2000784227 date "1999-07-01" @default.
• W2000784227 modified "2023-10-15" @default.
• W2000784227 title "Characterization of two members of a novel malic enzyme class" @default.
• W2000784227 cites W1491912808 @default.
• W2000784227 cites W1503540946 @default.
• W2000784227 cites W1505074673 @default.
• W2000784227 cites W1520565605 @default.
• W2000784227 cites W1542593497 @default.
• W2000784227 cites W1545833105 @default.
• W2000784227 cites W1602119380 @default.
• W2000784227 cites W1784734738 @default.
• W2000784227 cites W1869038516 @default.
• W2000784227 cites W1975144248 @default.
• W2000784227 cites W1976058456 @default.
• W2000784227 cites W1986559976 @default.
• W2000784227 cites W1987486786 @default.
• W2000784227 cites W1992993726 @default.
• W2000784227 cites W2010423759 @default.
• W2000784227 cites W2015258055 @default.
• W2000784227 cites W2031607883 @default.
• W2000784227 cites W2031709720 @default.
• W2000784227 cites W2038524754 @default.
• W2000784227 cites W2046633653 @default.
• W2000784227 cites W2057061781 @default.
• W2000784227 cites W2058306763 @default.
• W2000784227 cites W2060868140 @default.
• W2000784227 cites W2062164019 @default.
• W2000784227 cites W2068738875 @default.
• W2000784227 cites W2070572040 @default.
• W2000784227 cites W2072726289 @default.
• W2000784227 cites W2080355037 @default.
• W2000784227 cites W2095591940 @default.
• W2000784227 cites W2100837269 @default.
• W2000784227 cites W2124554753 @default.
• W2000784227 cites W2425852108 @default.
• W2000784227 cites W3199747857 @default.
• W2000784227 cites W331981547 @default.
• W2000784227 cites W4293247451 @default.
• W2000784227 doi "https://doi.org/10.1016/s0167-4838(99)00112-0" @default.
• W2000784227 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10407149" @default.
• W2000784227 hasPublicationYear "1999" @default.
• W2000784227 type Work @default.
• W2000784227 sameAs 2000784227 @default.
• W2000784227 citedByCount "41" @default.
• W2000784227 countsByYear W20007842272012 @default.
• W2000784227 countsByYear W20007842272013 @default.
• W2000784227 countsByYear W20007842272014 @default.
• W2000784227 countsByYear W20007842272015 @default.
• W2000784227 countsByYear W20007842272016 @default.
• W2000784227 countsByYear W20007842272017 @default.
• W2000784227 countsByYear W20007842272018 @default.
• W2000784227 countsByYear W20007842272019 @default.
• W2000784227 countsByYear W20007842272020 @default.
• W2000784227 countsByYear W20007842272021 @default.
• W2000784227 crossrefType "journal-article" @default.
• W2000784227 hasAuthorship W2000784227A5000015314 @default.
• W2000784227 hasAuthorship W2000784227A5031720116 @default.
• W2000784227 hasAuthorship W2000784227A5091657224 @default.
• W2000784227 hasConcept C119795356 @default.
• W2000784227 hasConcept C132901563 @default.
• W2000784227 hasConcept C181199279 @default.
• W2000784227 hasConcept C185592680 @default.
• W2000784227 hasConcept C2776317432 @default.
• W2000784227 hasConcept C2778957662 @default.
• W2000784227 hasConcept C2779032678 @default.
• W2000784227 hasConcept C2780968799 @default.
• W2000784227 hasConcept C55493867 @default.
• W2000784227 hasConcept C71240020 @default.
• W2000784227 hasConcept C75520062 @default.
• W2000784227 hasConcept C86803240 @default.
• W2000784227 hasConceptScore W2000784227C119795356 @default.
• W2000784227 hasConceptScore W2000784227C132901563 @default.
• W2000784227 hasConceptScore W2000784227C181199279 @default.
• W2000784227 hasConceptScore W2000784227C185592680 @default.
• W2000784227 hasConceptScore W2000784227C2776317432 @default.
• W2000784227 hasConceptScore W2000784227C2778957662 @default.
• W2000784227 hasConceptScore W2000784227C2779032678 @default.
• W2000784227 hasConceptScore W2000784227C2780968799 @default.
• W2000784227 hasConceptScore W2000784227C55493867 @default.
• W2000784227 hasConceptScore W2000784227C71240020 @default.
• W2000784227 hasConceptScore W2000784227C75520062 @default.
• W2000784227 hasConceptScore W2000784227C86803240 @default.
• W2000784227 hasIssue "2" @default.
• W2000784227 hasLocation W20007842271 @default.
• W2000784227 hasLocation W20007842272 @default.
• W2000784227 hasOpenAccess W2000784227 @default.
• W2000784227 hasPrimaryLocation W20007842271 @default.
• W2000784227 hasRelatedWork W1989149983 @default.
• W2000784227 hasRelatedWork W1992133830 @default.
• W2000784227 hasRelatedWork W2020688876 @default.
• W2000784227 hasRelatedWork W2026143944 @default.
• W2000784227 hasRelatedWork W2081301515 @default.
• W2000784227 hasRelatedWork W2083724967 @default.

• next