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- W2000784443 abstract "Phagocytic capacity of circulating neutrophils and monocytes was studied by electron micrsocopy in 2 children with Chèdiak-Higashi syndrome (CHS). Apparent phagocytosis of autologous leucocytes by the CHS neutrophils and monocytes was demonstrated when they were coincubated with Staphylococcus aureus in vitro, indicating their capacity for hyperactive phagocytosis. The hyperactive phagocytic capacity of the CHS phagocytes was a cellular abnormality. CHS neutrophils and monocytes are known to be defective in Chemotaxis and bactericidal capacity, and the hyperactive phagocytic capacity is another functional abnormality of CHS phagocytes." @default.
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- W2000784443 date "2009-04-24" @default.
- W2000784443 modified "2023-09-27" @default.
- W2000784443 title "Hyperactive phagocytosis by circulating neutrophils and monocytes in Chèdiak-Higashi syndrome" @default.
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- W2000784443 doi "https://doi.org/10.1111/j.1600-0609.1986.tb01791.x" @default.
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