Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000789922> ?p ?o ?g. }
- W2000789922 endingPage "9070" @default.
- W2000789922 startingPage "9061" @default.
- W2000789922 abstract "Optically active 3,4-disubsutituted azetidin-2-ones have been prepared by annelation of chiral silylimines derived from (S) or (R)-lactaldehyde with the ester enolate of the ethyl 2,2,5,5,-tetramethyl-1,2,5-azadisilolidin-1-acetate (STABASE). Oxidation of the hydroxyethyl side chain on the C-4 position of the β-lactam ring, followed by Baeyer-Villiger oxidation led to the optically active (3S, 4S ) 3-amino-4-acetoxy-β-laclam. The absolute configuration of this compound was determined by elaboration of this substrate to a key intermediate in the synthesis of the antibiotic “Aztreonam”. Nucleophilic displacement of the acetoxy group led to optically active 3-amino-4-alkyl (aryl)-azetidin-2-ones." @default.
- W2000789922 created "2016-06-24" @default.
- W2000789922 creator A5016790790 @default.
- W2000789922 creator A5018118490 @default.
- W2000789922 creator A5019001458 @default.
- W2000789922 creator A5054737469 @default.
- W2000789922 creator A5059791109 @default.
- W2000789922 creator A5071584442 @default.
- W2000789922 creator A5074334509 @default.
- W2000789922 date "1991-11-01" @default.
- W2000789922 modified "2023-10-06" @default.
- W2000789922 title "β-Lactams from ester enolates and silylimines: An enantiospecific synthesis of monocyclic β-lactams." @default.
- W2000789922 cites W1956405536 @default.
- W2000789922 cites W1965410684 @default.
- W2000789922 cites W1966911646 @default.
- W2000789922 cites W1967163437 @default.
- W2000789922 cites W1971641023 @default.
- W2000789922 cites W1980311020 @default.
- W2000789922 cites W1992365652 @default.
- W2000789922 cites W1993563654 @default.
- W2000789922 cites W1994181189 @default.
- W2000789922 cites W1997025574 @default.
- W2000789922 cites W1998001943 @default.
- W2000789922 cites W2014252895 @default.
- W2000789922 cites W2017191752 @default.
- W2000789922 cites W2023380600 @default.
- W2000789922 cites W2028032656 @default.
- W2000789922 cites W2029425717 @default.
- W2000789922 cites W2031334705 @default.
- W2000789922 cites W2033195344 @default.
- W2000789922 cites W2033535445 @default.
- W2000789922 cites W2035521060 @default.
- W2000789922 cites W2039242812 @default.
- W2000789922 cites W2045465559 @default.
- W2000789922 cites W2053201451 @default.
- W2000789922 cites W2053897664 @default.
- W2000789922 cites W2072358422 @default.
- W2000789922 cites W2081775133 @default.
- W2000789922 cites W2091221450 @default.
- W2000789922 cites W2105303519 @default.
- W2000789922 cites W2117486981 @default.
- W2000789922 cites W2140050612 @default.
- W2000789922 cites W2161275449 @default.
- W2000789922 cites W2164285511 @default.
- W2000789922 cites W2171719775 @default.
- W2000789922 cites W2333841215 @default.
- W2000789922 cites W2334825023 @default.
- W2000789922 cites W2368377705 @default.
- W2000789922 cites W2403875939 @default.
- W2000789922 cites W2517871118 @default.
- W2000789922 cites W2949309941 @default.
- W2000789922 cites W2949834136 @default.
- W2000789922 cites W2952345765 @default.
- W2000789922 cites W2952832036 @default.
- W2000789922 cites W2952920687 @default.
- W2000789922 doi "https://doi.org/10.1016/s0040-4020(01)86509-1" @default.
- W2000789922 hasPublicationYear "1991" @default.
- W2000789922 type Work @default.
- W2000789922 sameAs 2000789922 @default.
- W2000789922 citedByCount "31" @default.
- W2000789922 countsByYear W20007899222017 @default.
- W2000789922 countsByYear W20007899222018 @default.
- W2000789922 countsByYear W20007899222023 @default.
- W2000789922 crossrefType "journal-article" @default.
- W2000789922 hasAuthorship W2000789922A5016790790 @default.
- W2000789922 hasAuthorship W2000789922A5018118490 @default.
- W2000789922 hasAuthorship W2000789922A5019001458 @default.
- W2000789922 hasAuthorship W2000789922A5054737469 @default.
- W2000789922 hasAuthorship W2000789922A5059791109 @default.
- W2000789922 hasAuthorship W2000789922A5071584442 @default.
- W2000789922 hasAuthorship W2000789922A5074334509 @default.
- W2000789922 hasConcept C146686406 @default.
- W2000789922 hasConcept C161790260 @default.
- W2000789922 hasConcept C178790620 @default.
- W2000789922 hasConcept C178907741 @default.
- W2000789922 hasConcept C185592680 @default.
- W2000789922 hasConcept C20774148 @default.
- W2000789922 hasConcept C25170562 @default.
- W2000789922 hasConcept C2776131168 @default.
- W2000789922 hasConcept C2780263894 @default.
- W2000789922 hasConcept C2780378348 @default.
- W2000789922 hasConcept C2781076698 @default.
- W2000789922 hasConcept C3019471444 @default.
- W2000789922 hasConcept C71240020 @default.
- W2000789922 hasConceptScore W2000789922C146686406 @default.
- W2000789922 hasConceptScore W2000789922C161790260 @default.
- W2000789922 hasConceptScore W2000789922C178790620 @default.
- W2000789922 hasConceptScore W2000789922C178907741 @default.
- W2000789922 hasConceptScore W2000789922C185592680 @default.
- W2000789922 hasConceptScore W2000789922C20774148 @default.
- W2000789922 hasConceptScore W2000789922C25170562 @default.
- W2000789922 hasConceptScore W2000789922C2776131168 @default.
- W2000789922 hasConceptScore W2000789922C2780263894 @default.
- W2000789922 hasConceptScore W2000789922C2780378348 @default.
- W2000789922 hasConceptScore W2000789922C2781076698 @default.
- W2000789922 hasConceptScore W2000789922C3019471444 @default.
- W2000789922 hasConceptScore W2000789922C71240020 @default.
- W2000789922 hasIssue "43" @default.