Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000792397> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2000792397 endingPage "818" @default.
- W2000792397 startingPage "815" @default.
- W2000792397 abstract "Previous studies have shown significant correlations between interferon (IFN) induced enhancement of the enzyme 2',5'-oligoadenylate (2',5'-A) synthetase in vitro and response to IFN therapy. A limitation of this and other predictive tests is the availability of malignant cells for culture. Malignant cells can be obtained from most palpable solid tumours by fine-needle aspiration. We investigated whether malignant cells from such aspirations can be used in a 2',5'-A synthetase assay. In 23/27 (85%) of the cases sufficient amounts of viable cells were obtained, containing a high proportion (greater than or equal to 90%) of tumour cells. In 13/23 tumour samples (57%) IFN-alpha significantly enhanced the 2',5'-A synthetase levels. The use of cells from the fine-needle aspirations for prediction of IFN sensitivity, makes the 2',5'-A synthetase test applicable in a wide range of tumours at a variety of disease stages." @default.
- W2000792397 created "2016-06-24" @default.
- W2000792397 creator A5026065105 @default.
- W2000792397 creator A5026545181 @default.
- W2000792397 creator A5043167781 @default.
- W2000792397 creator A5077719811 @default.
- W2000792397 date "1992-04-01" @default.
- W2000792397 modified "2023-09-23" @default.
- W2000792397 title "Measurement of interferon sensitivity in tumour cells from fine-needle aspirations" @default.
- W2000792397 cites W2065308713 @default.
- W2000792397 cites W2085245589 @default.
- W2000792397 cites W2086133857 @default.
- W2000792397 cites W2127725661 @default.
- W2000792397 cites W2128202926 @default.
- W2000792397 cites W2394887496 @default.
- W2000792397 cites W2416213844 @default.
- W2000792397 doi "https://doi.org/10.1016/0959-8049(92)90121-h" @default.
- W2000792397 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1524900" @default.
- W2000792397 hasPublicationYear "1992" @default.
- W2000792397 type Work @default.
- W2000792397 sameAs 2000792397 @default.
- W2000792397 citedByCount "1" @default.
- W2000792397 crossrefType "journal-article" @default.
- W2000792397 hasAuthorship W2000792397A5026065105 @default.
- W2000792397 hasAuthorship W2000792397A5026545181 @default.
- W2000792397 hasAuthorship W2000792397A5043167781 @default.
- W2000792397 hasAuthorship W2000792397A5077719811 @default.
- W2000792397 hasConcept C121608353 @default.
- W2000792397 hasConcept C126322002 @default.
- W2000792397 hasConcept C142724271 @default.
- W2000792397 hasConcept C153911025 @default.
- W2000792397 hasConcept C181199279 @default.
- W2000792397 hasConcept C185592680 @default.
- W2000792397 hasConcept C202751555 @default.
- W2000792397 hasConcept C203014093 @default.
- W2000792397 hasConcept C2776178377 @default.
- W2000792397 hasConcept C2780841837 @default.
- W2000792397 hasConcept C3019684167 @default.
- W2000792397 hasConcept C3020380090 @default.
- W2000792397 hasConcept C502942594 @default.
- W2000792397 hasConcept C54355233 @default.
- W2000792397 hasConcept C55493867 @default.
- W2000792397 hasConcept C71924100 @default.
- W2000792397 hasConcept C81885089 @default.
- W2000792397 hasConcept C86803240 @default.
- W2000792397 hasConceptScore W2000792397C121608353 @default.
- W2000792397 hasConceptScore W2000792397C126322002 @default.
- W2000792397 hasConceptScore W2000792397C142724271 @default.
- W2000792397 hasConceptScore W2000792397C153911025 @default.
- W2000792397 hasConceptScore W2000792397C181199279 @default.
- W2000792397 hasConceptScore W2000792397C185592680 @default.
- W2000792397 hasConceptScore W2000792397C202751555 @default.
- W2000792397 hasConceptScore W2000792397C203014093 @default.
- W2000792397 hasConceptScore W2000792397C2776178377 @default.
- W2000792397 hasConceptScore W2000792397C2780841837 @default.
- W2000792397 hasConceptScore W2000792397C3019684167 @default.
- W2000792397 hasConceptScore W2000792397C3020380090 @default.
- W2000792397 hasConceptScore W2000792397C502942594 @default.
- W2000792397 hasConceptScore W2000792397C54355233 @default.
- W2000792397 hasConceptScore W2000792397C55493867 @default.
- W2000792397 hasConceptScore W2000792397C71924100 @default.
- W2000792397 hasConceptScore W2000792397C81885089 @default.
- W2000792397 hasConceptScore W2000792397C86803240 @default.
- W2000792397 hasIssue "4-5" @default.
- W2000792397 hasLocation W20007923971 @default.
- W2000792397 hasLocation W20007923972 @default.
- W2000792397 hasOpenAccess W2000792397 @default.
- W2000792397 hasPrimaryLocation W20007923971 @default.
- W2000792397 hasRelatedWork W1972814835 @default.
- W2000792397 hasRelatedWork W1981885332 @default.
- W2000792397 hasRelatedWork W2033530968 @default.
- W2000792397 hasRelatedWork W2071984357 @default.
- W2000792397 hasRelatedWork W2392254804 @default.
- W2000792397 hasRelatedWork W2399420121 @default.
- W2000792397 hasRelatedWork W2401541974 @default.
- W2000792397 hasRelatedWork W2946316715 @default.
- W2000792397 hasRelatedWork W35629616 @default.
- W2000792397 hasRelatedWork W120488427 @default.
- W2000792397 hasVolume "28" @default.
- W2000792397 isParatext "false" @default.
- W2000792397 isRetracted "false" @default.
- W2000792397 magId "2000792397" @default.
- W2000792397 workType "article" @default.