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- W2000793480 abstract "Human herpesviruses 6A, 6B, and 7 (HHV-6A, HHV-6B, and HHV-7) are classified within the roseolovirus genus of the betaherpesvirus subfamily. Most humans likely harbor at least two of these large DNA viruses, and 1% of humans harbor germline chromosomally integrated (ci) HHV-6A or HHV-6B genomes. Differences at the genetic level manifest as distinct biologic properties during infection and disease. We provide a brief synopsis of roseolovirus replication and highlight the unique properties of their lifecycle and what is known about the viral gene products that mediate these functions. In the nearly 30 years since their discovery, we have only begun to unlock the molecular strategies these highly evolved pathogens employ to establish and maintain chronic infections in humans." @default.
- W2000793480 created "2016-06-24" @default.
- W2000793480 creator A5009748553 @default.
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- W2000793480 date "2014-12-01" @default.
- W2000793480 modified "2023-10-18" @default.
- W2000793480 title "Roseolovirus molecular biology: recent advances" @default.
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- W2000793480 doi "https://doi.org/10.1016/j.coviro.2014.10.004" @default.
- W2000793480 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4753783" @default.
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