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- W2000800038 endingPage "414" @default.
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- W2000800038 abstract "The incidence of neurological diseases of unknown etiology is increasing, including well-studied diseases such as Alzhiemer's, Parkinson's, and multiple sclerosis. The blood-brain barrier provides protection for the brain but also hinders the treatment and diagnosis of these neurological diseases, because the drugs must cross the blood-brain barrier to reach the lesions. Thus, attention has turned to developing novel and effective delivery systems that are capable of carrying drug and that provide good bioavailability in the brain. Nanoneurotechnology, particularly application of nanoparticles in drug delivery, has provided promising answers to some of these issues in recent years. Here we review the recent advances in the understanding of several common forms of neurological diseases and particularly the applications of nanoparticles to treat and diagnose them. In addition, we discuss the integration of bioinformatics and modern genomic approaches in the development of nanoparticles.In this review paper, applications of nanotechnology-based diagnostic methods and therapeutic modalities are discussed addressing a variety of neurological disorders, with special attention to blood-brain barrier delivery methods. These novel nanomedicine approaches are expected to revolutionize several aspects of clinical neurology." @default.
- W2000800038 created "2016-06-24" @default.
- W2000800038 creator A5007578920 @default.
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- W2000800038 creator A5051482334 @default.
- W2000800038 creator A5058413340 @default.
- W2000800038 creator A5088923237 @default.
- W2000800038 date "2012-05-01" @default.
- W2000800038 modified "2023-10-06" @default.
- W2000800038 title "Nanoparticles in the treatment and diagnosis of neurological disorders: untamed dragon with fire power to heal" @default.
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