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- W2000807963 abstract "Objective: To study the association of a multimodal pain protocol (MMPC) and reduced hospital stay after open abdominal hysterectomy. Study design: The study design was a comparison of a prospective cohort with a retrospective historical control. We enrolled endometrial cancer patients undergoing open abdominal hysterectomy with lymphadenectomy by the same surgeon. Control patients from 2008 to 2010 who received morphine PCA alone were compared with a similar demographic group of patients from 2011 to 2013 who received MMPC. MMPC consisted of gabapentin (900 mg PO) and acetaminophen (1 g IV) administered 45–60 min preoperatively. The surgical site was injected with bupivacaine with 0.5% epinephrine prior to incision. The postoperative pain control regimen consisted of gabapentin (300 mg PO every 6 h), acetaminophen (1 g IV every 8 h for 24 h postoperatively), ketorolac (15 mg IV every 6 h for 48 h postoperatively), morphine PCA (2 mg IV every 10 min, no basal rate) and oxycodone/acetaminophen (10/325 mg PO every 6 h as needed). Results: Length of hospital stay (LOH) of the study cohort (N = 105 with MMPC) was compared with the historical with postoperative morphine alone (N = 113 without MMPC). There were no differences in demographic, uterine cancer stage, or comorbidities between the two arms. The LOH was 1.6 days for patients receiving MMPC and 3.3 days for patients who received morphine alone (P < 0.001). Conclusion: Multimodal pain control is associated with significantly reduced hospital stay after open abdominal hysterectomy. 2014 Elsevier Ireland Ltd. All rights reserved." @default.
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- W2000807963 date "2015-04-01" @default.
- W2000807963 modified "2023-09-27" @default.
- W2000807963 title "Multimodal pain control is associated with reduced hospital stay following open abdominal hysterectomy" @default.
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- W2000807963 doi "https://doi.org/10.1016/j.ygyno.2015.01.483" @default.
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