Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000825873> ?p ?o ?g. }
- W2000825873 endingPage "1501" @default.
- W2000825873 startingPage "1491" @default.
- W2000825873 abstract "Postischemic cerebral blood flow and blood volume changes have been associated with angiogenesis; nevertheless, the spatiotemporal changes in vascular permeability, vascular density, and vessel size have not been investigated. Here we report a prolonged increase in vascular permeability from day 3 to day 21 after ischemia, in particular in the reperfused outer cortical layers and leptomeninges. Increased cerebral blood volume (CBV) was observed from day 3 to day 14, whereas increased blood volume in small vessels, primarily capillaries, was noticed from day 7 to day 14 in the reperfused cortex. An initial decrease in vascular density and a reciprocal increase in vessel size were observed within the reperfused cortex at days 1 and 3 after ischemia. Immunohistological analysis confirmed a similar decrease in microvessel density and an increase in vessel size in vessels with a diameter greater than 30 μm. These large-sized vessels exhibited intense basic fibroblast growth factor and endothelial nitric oxide synthase immunoreactivity, suggesting the growth of collateral vessels. By contrast, a late increase in vascular density was noticed in the reperfused outer cortex at days 14 and 21 after ischemia. Together, these findings suggest that the early phase of CBV increase is likely because of the improvement in collateral circulation, whereas the late phase of CBV increase is attributed to the surge of angiogenesis." @default.
- W2000825873 created "2016-06-24" @default.
- W2000825873 creator A5002281616 @default.
- W2000825873 creator A5019380971 @default.
- W2000825873 creator A5038962078 @default.
- W2000825873 creator A5047902750 @default.
- W2000825873 creator A5063365781 @default.
- W2000825873 creator A5083684844 @default.
- W2000825873 creator A5087272338 @default.
- W2000825873 creator A5090797588 @default.
- W2000825873 date "2008-05-14" @default.
- W2000825873 modified "2023-10-16" @default.
- W2000825873 title "Dynamic Changes in Vascular Permeability, Cerebral Blood Volume, Vascular Density, and Size after Transient Focal Cerebral Ischemia in Rats: Evaluation with Contrast-Enhanced Magnetic Resonance Imaging" @default.
- W2000825873 cites W1964426997 @default.
- W2000825873 cites W1964908223 @default.
- W2000825873 cites W1984338166 @default.
- W2000825873 cites W1988052993 @default.
- W2000825873 cites W1988155976 @default.
- W2000825873 cites W1998080268 @default.
- W2000825873 cites W2002479267 @default.
- W2000825873 cites W2006041148 @default.
- W2000825873 cites W2009485585 @default.
- W2000825873 cites W2011875859 @default.
- W2000825873 cites W2013979525 @default.
- W2000825873 cites W2016324413 @default.
- W2000825873 cites W2019540655 @default.
- W2000825873 cites W2021124405 @default.
- W2000825873 cites W2023250693 @default.
- W2000825873 cites W2036472881 @default.
- W2000825873 cites W2036827636 @default.
- W2000825873 cites W2039559957 @default.
- W2000825873 cites W2043052859 @default.
- W2000825873 cites W2050549465 @default.
- W2000825873 cites W2055447603 @default.
- W2000825873 cites W2060560910 @default.
- W2000825873 cites W2065977830 @default.
- W2000825873 cites W2071893373 @default.
- W2000825873 cites W2090148529 @default.
- W2000825873 cites W2092241676 @default.
- W2000825873 cites W2092654563 @default.
- W2000825873 cites W2093062161 @default.
- W2000825873 cites W2100186853 @default.
- W2000825873 cites W2108610949 @default.
- W2000825873 cites W2111620238 @default.
- W2000825873 cites W2118309500 @default.
- W2000825873 cites W2129282529 @default.
- W2000825873 cites W2141851994 @default.
- W2000825873 cites W2142835803 @default.
- W2000825873 cites W2149261049 @default.
- W2000825873 cites W2152091665 @default.
- W2000825873 cites W2154525168 @default.
- W2000825873 cites W2166615294 @default.
- W2000825873 cites W4240511213 @default.
- W2000825873 doi "https://doi.org/10.1038/jcbfm.2008.42" @default.
- W2000825873 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18478021" @default.
- W2000825873 hasPublicationYear "2008" @default.
- W2000825873 type Work @default.
- W2000825873 sameAs 2000825873 @default.
- W2000825873 citedByCount "107" @default.
- W2000825873 countsByYear W20008258732012 @default.
- W2000825873 countsByYear W20008258732013 @default.
- W2000825873 countsByYear W20008258732014 @default.
- W2000825873 countsByYear W20008258732015 @default.
- W2000825873 countsByYear W20008258732016 @default.
- W2000825873 countsByYear W20008258732017 @default.
- W2000825873 countsByYear W20008258732018 @default.
- W2000825873 countsByYear W20008258732019 @default.
- W2000825873 countsByYear W20008258732020 @default.
- W2000825873 countsByYear W20008258732021 @default.
- W2000825873 countsByYear W20008258732022 @default.
- W2000825873 countsByYear W20008258732023 @default.
- W2000825873 crossrefType "journal-article" @default.
- W2000825873 hasAuthorship W2000825873A5002281616 @default.
- W2000825873 hasAuthorship W2000825873A5019380971 @default.
- W2000825873 hasAuthorship W2000825873A5038962078 @default.
- W2000825873 hasAuthorship W2000825873A5047902750 @default.
- W2000825873 hasAuthorship W2000825873A5063365781 @default.
- W2000825873 hasAuthorship W2000825873A5083684844 @default.
- W2000825873 hasAuthorship W2000825873A5087272338 @default.
- W2000825873 hasAuthorship W2000825873A5090797588 @default.
- W2000825873 hasConcept C105702510 @default.
- W2000825873 hasConcept C113045295 @default.
- W2000825873 hasConcept C119671327 @default.
- W2000825873 hasConcept C126322002 @default.
- W2000825873 hasConcept C142724271 @default.
- W2000825873 hasConcept C157767197 @default.
- W2000825873 hasConcept C158846371 @default.
- W2000825873 hasConcept C2776436680 @default.
- W2000825873 hasConcept C2777663904 @default.
- W2000825873 hasConcept C2778271429 @default.
- W2000825873 hasConcept C2780394083 @default.
- W2000825873 hasConcept C2781041448 @default.
- W2000825873 hasConcept C37557685 @default.
- W2000825873 hasConcept C541997718 @default.
- W2000825873 hasConcept C71924100 @default.
- W2000825873 hasConceptScore W2000825873C105702510 @default.
- W2000825873 hasConceptScore W2000825873C113045295 @default.
- W2000825873 hasConceptScore W2000825873C119671327 @default.