FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000826816> ?p ?o ?g. }

• W2000826816 endingPage "225" @default.
• W2000826816 startingPage "219" @default.
• W2000826816 abstract "We tested the hypothesis that D-arginine (D-Arg), which is not a substrate for nitric oxide synthase but scavenges reactive oxygen in vitro, is protective in vivo.Rats were made hypertensive by administering angiotensin II (Ang II) (0.7mg kg(-1) per day) for 7 days (Ang II group). Two other groups additionally received either 3 mmol D-Arg (Ang II + D-Arg group) or vitamin C (1g) (Ang II + Vit C group) per day. Sham-operated animals served as controls (n = 6-9). Systolic blood pressure was monitored daily and cardiovascular function determined ex vivo at 7 days.Ang II raised systolic blood pressure to 184mmHg, the increase was slightly attenuated by D-Arg treatment (-17mmHg; P < 0.05 versus Ang II alone) and prevented by Vit C. Acetylcholine-induced coronary relaxation was impaired in the Ang II group (P < 0.05 versus sham), the impairment was no different in the Ang II + D-Arg group, but prevented by Vit C. Likewise, Vit C but not D-Arg ameliorated reperfusion endothelium-dependent relaxation. However, in aortic rings D-Arg slightly improved acetylcholine relaxation (P < 0.05). Oxidative stress load estimated in plasma with thiobarbituric acid reactive substance was higher in the Ang II than the sham group, Vit C abolished the increase, but D-Arg was without effect.D-Arg is weakly antihypertensive in vivo and ameliorates aortic, but not coronary endothelium-dependent relaxation ex vivo. Because D-Arg had no effect on plasma oxidant status, this protection appears to be independent of reactive oxygen scavenging activity." @default.
• W2000826816 created "2016-06-24" @default.
• W2000826816 creator A5005229074 @default.
• W2000826816 creator A5034916813 @default.
• W2000826816 creator A5049169766 @default.
• W2000826816 date "2004-10-01" @default.
• W2000826816 modified "2023-09-27" @default.
• W2000826816 title "In vivo administration of d-arginine: effects on blood pressure and vascular function in angiotensin II-induced hypertensive rats" @default.
• W2000826816 cites W1976555160 @default.
• W2000826816 cites W1977469444 @default.
• W2000826816 cites W1991309815 @default.
• W2000826816 cites W1994950364 @default.
• W2000826816 cites W2000911595 @default.
• W2000826816 cites W2004028251 @default.
• W2000826816 cites W2013529909 @default.
• W2000826816 cites W2018598048 @default.
• W2000826816 cites W2021994429 @default.
• W2000826816 cites W2022330306 @default.
• W2000826816 cites W2022574364 @default.
• W2000826816 cites W2024839012 @default.
• W2000826816 cites W2033974115 @default.
• W2000826816 cites W2082594191 @default.
• W2000826816 cites W2085137779 @default.
• W2000826816 cites W2092091468 @default.
• W2000826816 cites W2110182057 @default.
• W2000826816 cites W2114547396 @default.
• W2000826816 cites W2118092557 @default.
• W2000826816 cites W2126085531 @default.
• W2000826816 cites W2131674562 @default.
• W2000826816 cites W2137017179 @default.
• W2000826816 cites W2152475686 @default.
• W2000826816 cites W2154972654 @default.
• W2000826816 cites W2159172002 @default.
• W2000826816 cites W2162138428 @default.
• W2000826816 cites W2172139851 @default.
• W2000826816 cites W4252157436 @default.
• W2000826816 doi "https://doi.org/10.1016/j.atherosclerosis.2004.05.016" @default.
• W2000826816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15380443" @default.
• W2000826816 hasPublicationYear "2004" @default.
• W2000826816 type Work @default.
• W2000826816 sameAs 2000826816 @default.
• W2000826816 citedByCount "7" @default.
• W2000826816 countsByYear W20008268162012 @default.
• W2000826816 countsByYear W20008268162020 @default.
• W2000826816 countsByYear W20008268162022 @default.
• W2000826816 crossrefType "journal-article" @default.
• W2000826816 hasAuthorship W2000826816A5005229074 @default.
• W2000826816 hasAuthorship W2000826816A5034916813 @default.
• W2000826816 hasAuthorship W2000826816A5049169766 @default.
• W2000826816 hasConcept C126322002 @default.
• W2000826816 hasConcept C134018914 @default.
• W2000826816 hasConcept C150903083 @default.
• W2000826816 hasConcept C185592680 @default.
• W2000826816 hasConcept C202751555 @default.
• W2000826816 hasConcept C207001950 @default.
• W2000826816 hasConcept C26291073 @default.
• W2000826816 hasConcept C2775910092 @default.
• W2000826816 hasConcept C2776151105 @default.
• W2000826816 hasConcept C2908929049 @default.
• W2000826816 hasConcept C48349386 @default.
• W2000826816 hasConcept C519581460 @default.
• W2000826816 hasConcept C55493867 @default.
• W2000826816 hasConcept C71924100 @default.
• W2000826816 hasConcept C84393581 @default.
• W2000826816 hasConcept C86803240 @default.
• W2000826816 hasConceptScore W2000826816C126322002 @default.
• W2000826816 hasConceptScore W2000826816C134018914 @default.
• W2000826816 hasConceptScore W2000826816C150903083 @default.
• W2000826816 hasConceptScore W2000826816C185592680 @default.
• W2000826816 hasConceptScore W2000826816C202751555 @default.
• W2000826816 hasConceptScore W2000826816C207001950 @default.
• W2000826816 hasConceptScore W2000826816C26291073 @default.
• W2000826816 hasConceptScore W2000826816C2775910092 @default.
• W2000826816 hasConceptScore W2000826816C2776151105 @default.
• W2000826816 hasConceptScore W2000826816C2908929049 @default.
• W2000826816 hasConceptScore W2000826816C48349386 @default.
• W2000826816 hasConceptScore W2000826816C519581460 @default.
• W2000826816 hasConceptScore W2000826816C55493867 @default.
• W2000826816 hasConceptScore W2000826816C71924100 @default.
• W2000826816 hasConceptScore W2000826816C84393581 @default.
• W2000826816 hasConceptScore W2000826816C86803240 @default.
• W2000826816 hasIssue "2" @default.
• W2000826816 hasLocation W20008268161 @default.
• W2000826816 hasLocation W20008268162 @default.
• W2000826816 hasOpenAccess W2000826816 @default.
• W2000826816 hasPrimaryLocation W20008268161 @default.
• W2000826816 hasRelatedWork W1966234050 @default.
• W2000826816 hasRelatedWork W1993142192 @default.
• W2000826816 hasRelatedWork W2047925791 @default.
• W2000826816 hasRelatedWork W2076343727 @default.
• W2000826816 hasRelatedWork W2077960701 @default.
• W2000826816 hasRelatedWork W2107563524 @default.
• W2000826816 hasRelatedWork W2116962665 @default.
• W2000826816 hasRelatedWork W2151139437 @default.
• W2000826816 hasRelatedWork W2171089442 @default.
• W2000826816 hasRelatedWork W2748952813 @default.
• W2000826816 hasVolume "176" @default.
• W2000826816 isParatext "false" @default.

• next