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• W2000827986 abstract "Vitamin D insufficiency is characterized, since 2005, by 25(OH)D concentration less than 75 nmol/L (or 30 ng/mL). Vitamin D could interfere with many mechanisms involved in preeclampsia's pathogenesis including trophoblastic invasion and immunomodulation as well as blood pressure control and proteinuria. Occurrence of preeclampsia and gestational diabetes seems to be linked to vitamin D deficiency but recent data in the literature are contradictory. Vitamin D supplementation during pregnancy is controversial. Some societies consider it unnecessary and others recommend up to 2000 UI/d. There is no reported case of teratogenicity linked with vitamin D intake. L’insuffisance en vitamine D est définie depuis 2005 par des concentrations en 25(OH)D inférieures à 75 nmol/L (ou 30 ng/mL). La vitamine D peut théoriquement interférer avec de nombreux mécanismes connus dans la pathogénie de la pré-éclampsie (PE) : invasion trophoblastique et implantation, angiogenèse, immunomodulation, inflammation, régulation de la pression artérielle, et contrôle de la protéinurie. Il semble exister un lien entre déficit en vitamine D, PE et diabète gestationnel, mais les résultats de la littérature récente sont contradictoires. La supplémentation en vitamine D pendant la grossesse est également controversée. Certaines sociétés savantes ne la recommandent pas et d’autres préconisent de donner jusqu’à 2000 UI/j. Il n’y a pas de cas de tératogénicité rapporté à la prise de vitamine D." @default.
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• W2000827986 date "2013-10-01" @default.
• W2000827986 modified "2023-10-18" @default.
• W2000827986 title "Vitamine D et grossesse" @default.
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• W2000827986 doi "https://doi.org/10.1016/j.lpm.2013.07.007" @default.
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