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- W2000828505 abstract "During eye formation, inductive phenomena occurring between retinal pigmented epithelium (RPE) and retina are not well understood. After briefly summarizing the normal development of retina and RPE, we present three-dimensionalin vitromodels of the chick embryonic retina which allows elucidation of RPE–retina interactions. In suchretinospheroids, a complete arrangement of layers is achieved, provided that dispersed retinal cells are: (1) young enough; and (2) reaggregated on a monolayer of RPE. Thereby, the RPE extends cell proliferation, while differentiation is much delayed. These findings assign to the RPE a decisive role for the genesis and regeneration of a vertebrate retina." @default.
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- W2000828505 date "1998-06-01" @default.
- W2000828505 modified "2023-10-03" @default.
- W2000828505 title "Inductive effects of the retinal pigmented epithelium (RPE) on histogenesis of the avian retina as revealed by retinospheroid technology" @default.
- W2000828505 doi "https://doi.org/10.1006/scdb.1998.0234" @default.
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