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• W2000834293 abstract "The prolongation of P-wave duration has long been shown to indicate the presence of high risk for atrial fibrillation. The circadian variation of P-wave characteristics and their dynamic adaptation to heart rate changes was not tested before.To evaluate the diurnal pattern of P-wave duration, P area, and PR interval and of their linearly fitted relation with RR interval, 50 healthy volunteers (25 men, mean age 34 +/- 10 years) underwent 24-hour ambulatory electrocardiographic (ECG) recording with digital 12-lead Holter recorders. The median P-wave duration, P area, and PR interval were calculated from the average 12-lead ECG constructed from each 10-second ECG recording. Single harmonic regression analysis was performed to reveal the presence of circadian variation in the aforementioned ECG parameters.The P area (P < 0.0001, R(2) = 0.78), the PR interval (P < 0.0001, R(2) = 0.92), the P area / RR slope (P < 0.0001, R(2) = 0.55), and the PR/RR slope (P < 0.0001, R(2) = 0.42) showed a highly significant circadian variation while the periodic nature of P-wave duration (P = 0.016, R(2) = 0.32) and of the P duration / RR slope (P = 0.011, R(2) = 0.18) was only indicated by harmonic regression analysis.P-wave duration, P area, and PR interval show a significant circadian variation in healthy subjects. The relations between P area/RR,PR/ RR, and P duration/RR also demonstrate a significant diurnal pattern." @default.
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• W2000834293 date "2001-04-01" @default.
• W2000834293 modified "2023-10-12" @default.
• W2000834293 title "Circadian Behavior of P-Wave Duration, P-Wave Area, and PR Interval in Healthy Subjects" @default.
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• W2000834293 doi "https://doi.org/10.1111/j.1542-474x.2001.tb00092.x" @default.
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