Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000837211> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- W2000837211 endingPage "677" @default.
- W2000837211 startingPage "673" @default.
- W2000837211 abstract "A new synthetic method for the preparation of the cholesterol-lowering drug simvastatin from the naturally occurring lovastatin is reported. The synthesis employs first the protection of the OH group of lovastatin (1) and then the protection of the lactone CO group to prevent enolization via conversion to the orthoesters 4a and 4b. Alkylation of the 2-methylbutyrate side chain is then successfully achieved. Removal of the protecting groups affords antihypercholesterolemic agent simvastatin (2)." @default.
- W2000837211 created "2016-06-24" @default.
- W2000837211 creator A5010819212 @default.
- W2000837211 creator A5070388057 @default.
- W2000837211 date "2003-03-01" @default.
- W2000837211 modified "2023-09-27" @default.
- W2000837211 title "A New Method for the Synthesis of Antihypercholesterolemic Agent Simvastatin" @default.
- W2000837211 doi "https://doi.org/10.1002/hlca.200390066" @default.
- W2000837211 hasPublicationYear "2003" @default.
- W2000837211 type Work @default.
- W2000837211 sameAs 2000837211 @default.
- W2000837211 citedByCount "5" @default.
- W2000837211 countsByYear W20008372112019 @default.
- W2000837211 countsByYear W20008372112023 @default.
- W2000837211 crossrefType "journal-article" @default.
- W2000837211 hasAuthorship W2000837211A5010819212 @default.
- W2000837211 hasAuthorship W2000837211A5070388057 @default.
- W2000837211 hasConcept C161790260 @default.
- W2000837211 hasConcept C164361826 @default.
- W2000837211 hasConcept C178790620 @default.
- W2000837211 hasConcept C185592680 @default.
- W2000837211 hasConcept C2776329913 @default.
- W2000837211 hasConcept C2778163477 @default.
- W2000837211 hasConcept C2780940807 @default.
- W2000837211 hasConcept C55493867 @default.
- W2000837211 hasConcept C71924100 @default.
- W2000837211 hasConcept C98274493 @default.
- W2000837211 hasConceptScore W2000837211C161790260 @default.
- W2000837211 hasConceptScore W2000837211C164361826 @default.
- W2000837211 hasConceptScore W2000837211C178790620 @default.
- W2000837211 hasConceptScore W2000837211C185592680 @default.
- W2000837211 hasConceptScore W2000837211C2776329913 @default.
- W2000837211 hasConceptScore W2000837211C2778163477 @default.
- W2000837211 hasConceptScore W2000837211C2780940807 @default.
- W2000837211 hasConceptScore W2000837211C55493867 @default.
- W2000837211 hasConceptScore W2000837211C71924100 @default.
- W2000837211 hasConceptScore W2000837211C98274493 @default.
- W2000837211 hasIssue "3" @default.
- W2000837211 hasLocation W20008372111 @default.
- W2000837211 hasOpenAccess W2000837211 @default.
- W2000837211 hasPrimaryLocation W20008372111 @default.
- W2000837211 hasRelatedWork W173003252 @default.
- W2000837211 hasRelatedWork W2019919093 @default.
- W2000837211 hasRelatedWork W2054598274 @default.
- W2000837211 hasRelatedWork W2075167633 @default.
- W2000837211 hasRelatedWork W2350674866 @default.
- W2000837211 hasRelatedWork W2385109554 @default.
- W2000837211 hasRelatedWork W2419183198 @default.
- W2000837211 hasRelatedWork W2893524270 @default.
- W2000837211 hasRelatedWork W4247367493 @default.
- W2000837211 hasRelatedWork W3092723996 @default.
- W2000837211 hasVolume "86" @default.
- W2000837211 isParatext "false" @default.
- W2000837211 isRetracted "false" @default.
- W2000837211 magId "2000837211" @default.
- W2000837211 workType "article" @default.