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• W2000841294 abstract "<b>Objective</b> To determine whether recurrence of leg ulcers may be prevented by surgical correction of superficial venous reflux in addition to compression. <b>Design</b> Randomised controlled trial. <b>Setting</b> Specialist nurse led leg ulcer clinics in three UK vascular centres. <b>Participants</b> 500 patients (500 legs) with open or recently healed leg ulcers and superficial venous reflux. <b>Interventions</b> Compression alone or compression plus saphenous surgery. <b>Main outcome measures</b> Primary outcomes were ulcer healing and ulcer recurrence. The secondary outcome was ulcer free time. <b>Results</b> Ulcer healing rates at three years were 89% for the compression group and 93% for the compression plus surgery group (P=0.73, log rank test). Rates of ulcer recurrence at four years were 56% for the compression group and 31% for the compression plus surgery group (P<0.01). For patients with isolated superficial reflux, recurrence rates at four years were 51% for the compression group and 27% for the compress plus surgery group (P<0.01). For patients who had superficial with segmental deep reflux, recurrence rates at three years were 52% for the compression group and 24% for the compression plus surgery group (P=0.04). For patients with superficial and total deep reflux, recurrence rates at three years were 46% for the compression group and 32% for the compression plus surgery group (P=0.33). Patients in the compression plus surgery group experienced a greater proportion of ulcer free time after three years compared with patients in the compression group (78% <i>v</i> 71%; P=0.007, Mann-Whitney U test). <b>Conclusion</b> Surgical correction of superficial venous reflux in addition to compression bandaging does not improve ulcer healing but reduces the recurrence of ulcers at four years and results in a greater proportion of ulcer free time. <b>Trial registration</b> Current Controlled Trials ISRCTN07549334." @default.
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• W2000841294 date "2007-06-01" @default.
• W2000841294 modified "2023-10-17" @default.
• W2000841294 title "Long term results of compression therapy alone versus compression plus surgery in chronic venous ulceration (ESCHAR): randomised controlled trial" @default.
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• W2000841294 doi "https://doi.org/10.1136/bmj.39216.542442.be" @default.
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