FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000843772> ?p ?o ?g. }

• W2000843772 endingPage "112" @default.
• W2000843772 startingPage "104" @default.
• W2000843772 abstract "Abdominal aortic aneurysm (AAA) pathogenesis remains poorly understood. This study investigated the gene expression profile of peripheral blood from patients with AAA using microarray technology.We determined gene expression profiles in pooled RNA from 10 AAA patients and 10 matched controls with arrays representing 14,000 transcripts. Microarray data for selected genes were confirmed by real-time PCR in two different AAA (n=36) and control (n=36) populations and integrated with biochemical data. We identified 91 genes which were differentially expressed in AAA patients. Gene Ontology analysis indicated a significant alteration of oxygen transport (increased hemoglobin gene expression) and lipid metabolism [including monoglyceride lipase and low density lipoprotein receptor-related protein 5 (LRP5) gene]. LRP5 expression was associated inversely with serum lipoprotein(a) [Lp(a)] concentration.Increased expression of hemoglobin chain genes as well as of genes involved in erythrocyte mechanical stability were observed in the AAA RNA pools. The association between low levels of LRP5 gene expression and increased levels of Lp(a) in AAA patients suggests a potential role of LRP5 in Lp(a) catabolism. Our data underline the power of microarrays in identifying further molecular perturbations associated with AAA." @default.
• W2000843772 created "2016-06-24" @default.
• W2000843772 creator A5006206653 @default.
• W2000843772 creator A5011842156 @default.
• W2000843772 creator A5012958988 @default.
• W2000843772 creator A5017215260 @default.
• W2000843772 creator A5020869832 @default.
• W2000843772 creator A5025147064 @default.
• W2000843772 creator A5041788136 @default.
• W2000843772 creator A5054768576 @default.
• W2000843772 creator A5057353647 @default.
• W2000843772 creator A5066969708 @default.
• W2000843772 date "2009-07-01" @default.
• W2000843772 modified "2023-10-16" @default.
• W2000843772 title "Gene Expression Profiling of Peripheral Blood in Patients with Abdominal Aortic Aneurysm" @default.
• W2000843772 cites W1817660875 @default.
• W2000843772 cites W1963931309 @default.
• W2000843772 cites W1964552106 @default.
• W2000843772 cites W1984874281 @default.
• W2000843772 cites W1992310713 @default.
• W2000843772 cites W1993788157 @default.
• W2000843772 cites W2002214040 @default.
• W2000843772 cites W2004454083 @default.
• W2000843772 cites W2019782788 @default.
• W2000843772 cites W2032601963 @default.
• W2000843772 cites W2037132744 @default.
• W2000843772 cites W2065678878 @default.
• W2000843772 cites W2071286923 @default.
• W2000843772 cites W2075037447 @default.
• W2000843772 cites W2085470748 @default.
• W2000843772 cites W2100668965 @default.
• W2000843772 cites W2104881638 @default.
• W2000843772 cites W2108491719 @default.
• W2000843772 cites W2128146309 @default.
• W2000843772 cites W2129179534 @default.
• W2000843772 cites W2135470349 @default.
• W2000843772 cites W2138512695 @default.
• W2000843772 cites W2150509784 @default.
• W2000843772 cites W2154825248 @default.
• W2000843772 cites W2165482500 @default.
• W2000843772 cites W2171307793 @default.
• W2000843772 cites W2570893955 @default.
• W2000843772 cites W4294107304 @default.
• W2000843772 doi "https://doi.org/10.1016/j.ejvs.2009.01.020" @default.
• W2000843772 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19233690" @default.
• W2000843772 hasPublicationYear "2009" @default.
• W2000843772 type Work @default.
• W2000843772 sameAs 2000843772 @default.
• W2000843772 citedByCount "43" @default.
• W2000843772 countsByYear W20008437722012 @default.
• W2000843772 countsByYear W20008437722013 @default.
• W2000843772 countsByYear W20008437722014 @default.
• W2000843772 countsByYear W20008437722015 @default.
• W2000843772 countsByYear W20008437722016 @default.
• W2000843772 countsByYear W20008437722017 @default.
• W2000843772 countsByYear W20008437722019 @default.
• W2000843772 countsByYear W20008437722020 @default.
• W2000843772 countsByYear W20008437722023 @default.
• W2000843772 crossrefType "journal-article" @default.
• W2000843772 hasAuthorship W2000843772A5006206653 @default.
• W2000843772 hasAuthorship W2000843772A5011842156 @default.
• W2000843772 hasAuthorship W2000843772A5012958988 @default.
• W2000843772 hasAuthorship W2000843772A5017215260 @default.
• W2000843772 hasAuthorship W2000843772A5020869832 @default.
• W2000843772 hasAuthorship W2000843772A5025147064 @default.
• W2000843772 hasAuthorship W2000843772A5041788136 @default.
• W2000843772 hasAuthorship W2000843772A5054768576 @default.
• W2000843772 hasAuthorship W2000843772A5057353647 @default.
• W2000843772 hasAuthorship W2000843772A5066969708 @default.
• W2000843772 hasBestOaLocation W20008437721 @default.
• W2000843772 hasConcept C104317684 @default.
• W2000843772 hasConcept C141071460 @default.
• W2000843772 hasConcept C150194340 @default.
• W2000843772 hasConcept C18431079 @default.
• W2000843772 hasConcept C186836561 @default.
• W2000843772 hasConcept C2776098176 @default.
• W2000843772 hasConcept C2779018089 @default.
• W2000843772 hasConcept C2779993416 @default.
• W2000843772 hasConcept C54355233 @default.
• W2000843772 hasConcept C71924100 @default.
• W2000843772 hasConcept C8415881 @default.
• W2000843772 hasConcept C86803240 @default.
• W2000843772 hasConceptScore W2000843772C104317684 @default.
• W2000843772 hasConceptScore W2000843772C141071460 @default.
• W2000843772 hasConceptScore W2000843772C150194340 @default.
• W2000843772 hasConceptScore W2000843772C18431079 @default.
• W2000843772 hasConceptScore W2000843772C186836561 @default.
• W2000843772 hasConceptScore W2000843772C2776098176 @default.
• W2000843772 hasConceptScore W2000843772C2779018089 @default.
• W2000843772 hasConceptScore W2000843772C2779993416 @default.
• W2000843772 hasConceptScore W2000843772C54355233 @default.
• W2000843772 hasConceptScore W2000843772C71924100 @default.
• W2000843772 hasConceptScore W2000843772C8415881 @default.
• W2000843772 hasConceptScore W2000843772C86803240 @default.
• W2000843772 hasIssue "1" @default.
• W2000843772 hasLocation W20008437721 @default.
• W2000843772 hasLocation W20008437722 @default.
• W2000843772 hasLocation W20008437723 @default.

• next