Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000848385> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2000848385 abstract "To investigate the hypothesis that high usage of clotting factor concentrate, rather than HIV infection, is the cause of immunodeficiency and AIDS in men with haemophilia.A comparison of AIDS defining conditions and CD4 counts in HIV positive and HIV negative patients with haemophilia matched for usage of clotting factor concentrate.A comprehensive care haemophilia centre.17 HIV positive and 17 HIV negative male patients with haemophilia A (age range 12-60 at beginning of study period) who had received similar amounts of clotting factor concentrate yearly over the years 1980-90.Clinical events listed as AIDS defining in the Centers for Disease Control AIDS definition; CD4 lymphocyte counts; death.Of 108 HIV positive male patients with haemophilia A, only 17 could be matched to an HIV negative patient. This was due to the much higher average usage of factor VIII in the HIV positive group. Between 1980 and 1990, 16 clinical events occurred in nine of the 17 HIV positive patients. No event occurred in the 17 HIV negative patients. In each pair the mean CD4 count during follow up was, on average, 0.5 x 10(9)/l lower in the HIV positive patient.These data reject the hypothesis that high usage of clotting factor concentrate, rather than HIV infection, is the cause of immunodeficiency and AIDS in men with haemophilia." @default.
- W2000848385 created "2016-06-24" @default.
- W2000848385 creator A5001593820 @default.
- W2000848385 creator A5004174170 @default.
- W2000848385 creator A5012630710 @default.
- W2000848385 creator A5019785892 @default.
- W2000848385 creator A5069063909 @default.
- W2000848385 creator A5081694461 @default.
- W2000848385 date "1996-01-27" @default.
- W2000848385 modified "2023-09-24" @default.
- W2000848385 title "Comparison of immunodeficiency and AIDS defining conditions in HIV negative and HIV postive men with haemophilia A" @default.
- W2000848385 cites W1969772237 @default.
- W2000848385 cites W1976892894 @default.
- W2000848385 cites W1980723902 @default.
- W2000848385 cites W1991829757 @default.
- W2000848385 cites W2006339880 @default.
- W2000848385 cites W2026056502 @default.
- W2000848385 cites W2075009428 @default.
- W2000848385 cites W2093734932 @default.
- W2000848385 cites W2108021400 @default.
- W2000848385 cites W2136723176 @default.
- W2000848385 cites W2412262898 @default.
- W2000848385 cites W52076583 @default.
- W2000848385 doi "https://doi.org/10.1136/bmj.312.7025.207" @default.
- W2000848385 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2349998" @default.
- W2000848385 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8563582" @default.
- W2000848385 hasPublicationYear "1996" @default.
- W2000848385 type Work @default.
- W2000848385 sameAs 2000848385 @default.
- W2000848385 citedByCount "9" @default.
- W2000848385 countsByYear W20008483852015 @default.
- W2000848385 crossrefType "journal-article" @default.
- W2000848385 hasAuthorship W2000848385A5001593820 @default.
- W2000848385 hasAuthorship W2000848385A5004174170 @default.
- W2000848385 hasAuthorship W2000848385A5012630710 @default.
- W2000848385 hasAuthorship W2000848385A5019785892 @default.
- W2000848385 hasAuthorship W2000848385A5069063909 @default.
- W2000848385 hasAuthorship W2000848385A5081694461 @default.
- W2000848385 hasBestOaLocation W20008483852 @default.
- W2000848385 hasConcept C126322002 @default.
- W2000848385 hasConcept C187212893 @default.
- W2000848385 hasConcept C203014093 @default.
- W2000848385 hasConcept C2777081929 @default.
- W2000848385 hasConcept C2777232031 @default.
- W2000848385 hasConcept C2777607303 @default.
- W2000848385 hasConcept C2778385053 @default.
- W2000848385 hasConcept C2780727368 @default.
- W2000848385 hasConcept C2781221834 @default.
- W2000848385 hasConcept C2992139802 @default.
- W2000848385 hasConcept C3013748606 @default.
- W2000848385 hasConcept C50440223 @default.
- W2000848385 hasConcept C71924100 @default.
- W2000848385 hasConcept C8891405 @default.
- W2000848385 hasConceptScore W2000848385C126322002 @default.
- W2000848385 hasConceptScore W2000848385C187212893 @default.
- W2000848385 hasConceptScore W2000848385C203014093 @default.
- W2000848385 hasConceptScore W2000848385C2777081929 @default.
- W2000848385 hasConceptScore W2000848385C2777232031 @default.
- W2000848385 hasConceptScore W2000848385C2777607303 @default.
- W2000848385 hasConceptScore W2000848385C2778385053 @default.
- W2000848385 hasConceptScore W2000848385C2780727368 @default.
- W2000848385 hasConceptScore W2000848385C2781221834 @default.
- W2000848385 hasConceptScore W2000848385C2992139802 @default.
- W2000848385 hasConceptScore W2000848385C3013748606 @default.
- W2000848385 hasConceptScore W2000848385C50440223 @default.
- W2000848385 hasConceptScore W2000848385C71924100 @default.
- W2000848385 hasConceptScore W2000848385C8891405 @default.
- W2000848385 hasLocation W20008483851 @default.
- W2000848385 hasLocation W20008483852 @default.
- W2000848385 hasLocation W20008483853 @default.
- W2000848385 hasLocation W20008483854 @default.
- W2000848385 hasOpenAccess W2000848385 @default.
- W2000848385 hasPrimaryLocation W20008483851 @default.
- W2000848385 hasRelatedWork W1560426713 @default.
- W2000848385 hasRelatedWork W2000848385 @default.
- W2000848385 hasRelatedWork W2028999303 @default.
- W2000848385 hasRelatedWork W2162791390 @default.
- W2000848385 hasRelatedWork W2186626202 @default.
- W2000848385 hasRelatedWork W2409010068 @default.
- W2000848385 hasRelatedWork W2472924350 @default.
- W2000848385 hasRelatedWork W2898647230 @default.
- W2000848385 hasRelatedWork W2991761618 @default.
- W2000848385 hasRelatedWork W97609995 @default.
- W2000848385 isParatext "false" @default.
- W2000848385 isRetracted "false" @default.
- W2000848385 magId "2000848385" @default.
- W2000848385 workType "article" @default.