Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000848907> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2000848907 endingPage "55" @default.
- W2000848907 startingPage "44" @default.
- W2000848907 abstract "1. Radioactive vitamin B12 was given by mouth to rats and baby pigs with and without binding and intrinsic factors. A few hours after dosing the greatest activity found in the wall of the gut was in the middle part of the small intestine and the area just distal to it. The amount of vitamin B12 in this area of the intestine was increased by materials that promoted, and decreased by those that inhibited, absorption. 2. A similar distribution in the gut wall was observed when vitamin B12 with or without binding or intrinsic factors was circulated through the small intestine of live anaesthetized rats for 1 h. In these circumstances, however, greater amounts were found in the carcase when the vitamin had not been deposited in the gut wall. 3. When similar perfusions were done with completely isolated small intestine of the rat the radioactivity that passed through the gut wall was all ultrafiltrable if rat stomach extract was in the circulating fluid. Only about 60% of the activity collected after perfusion with vitamin B12 alone or with Bendogen was ultrafiltrable. 4. Doses of labelled vitamin B12 placed directly into the caeca of rats and pigs and the colon of pigs were very poorly absorbed. 5. Preparations of mucosal cells from the middle segment of rat small intestine took up more vitamin B12 on incubation at 38° than did similar preparations from the proximal or distal segments. Uptake of vitamin B12 by the mucosal cells was enhanced by rat stomach extract and inhibited by Bendogen. 6. Vitamin B12 was detectable in the lymph collected from mesenteric or thoracic lymph ducts, but not in sufficient quantity to suggest that the lymphatic system is any more important a route of absorption than the blood stream" @default.
- W2000848907 created "2016-06-24" @default.
- W2000848907 creator A5001699734 @default.
- W2000848907 creator A5021873392 @default.
- W2000848907 date "1961-01-01" @default.
- W2000848907 modified "2023-09-27" @default.
- W2000848907 title "The absorption of vitamin B12 in animals II. The site of absorption of vitamin B12 and mode of action of intrinsic factor" @default.
- W2000848907 cites W1993446191 @default.
- W2000848907 cites W2009054670 @default.
- W2000848907 cites W2060393333 @default.
- W2000848907 cites W2087700041 @default.
- W2000848907 cites W2338495068 @default.
- W2000848907 doi "https://doi.org/10.1016/0009-8981(61)90035-3" @default.
- W2000848907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/13715246" @default.
- W2000848907 hasPublicationYear "1961" @default.
- W2000848907 type Work @default.
- W2000848907 sameAs 2000848907 @default.
- W2000848907 citedByCount "12" @default.
- W2000848907 countsByYear W20008489072023 @default.
- W2000848907 crossrefType "journal-article" @default.
- W2000848907 hasAuthorship W2000848907A5001699734 @default.
- W2000848907 hasAuthorship W2000848907A5021873392 @default.
- W2000848907 hasConcept C121332964 @default.
- W2000848907 hasConcept C125287762 @default.
- W2000848907 hasConcept C126322002 @default.
- W2000848907 hasConcept C134018914 @default.
- W2000848907 hasConcept C146957229 @default.
- W2000848907 hasConcept C185592680 @default.
- W2000848907 hasConcept C24890656 @default.
- W2000848907 hasConcept C2776940978 @default.
- W2000848907 hasConcept C2777569460 @default.
- W2000848907 hasConcept C2777882243 @default.
- W2000848907 hasConcept C2779422922 @default.
- W2000848907 hasConcept C2779750884 @default.
- W2000848907 hasConcept C2780829489 @default.
- W2000848907 hasConcept C55493867 @default.
- W2000848907 hasConcept C71924100 @default.
- W2000848907 hasConcept C86803240 @default.
- W2000848907 hasConceptScore W2000848907C121332964 @default.
- W2000848907 hasConceptScore W2000848907C125287762 @default.
- W2000848907 hasConceptScore W2000848907C126322002 @default.
- W2000848907 hasConceptScore W2000848907C134018914 @default.
- W2000848907 hasConceptScore W2000848907C146957229 @default.
- W2000848907 hasConceptScore W2000848907C185592680 @default.
- W2000848907 hasConceptScore W2000848907C24890656 @default.
- W2000848907 hasConceptScore W2000848907C2776940978 @default.
- W2000848907 hasConceptScore W2000848907C2777569460 @default.
- W2000848907 hasConceptScore W2000848907C2777882243 @default.
- W2000848907 hasConceptScore W2000848907C2779422922 @default.
- W2000848907 hasConceptScore W2000848907C2779750884 @default.
- W2000848907 hasConceptScore W2000848907C2780829489 @default.
- W2000848907 hasConceptScore W2000848907C55493867 @default.
- W2000848907 hasConceptScore W2000848907C71924100 @default.
- W2000848907 hasConceptScore W2000848907C86803240 @default.
- W2000848907 hasIssue "1" @default.
- W2000848907 hasLocation W20008489071 @default.
- W2000848907 hasLocation W20008489072 @default.
- W2000848907 hasOpenAccess W2000848907 @default.
- W2000848907 hasPrimaryLocation W20008489071 @default.
- W2000848907 hasRelatedWork W1947642682 @default.
- W2000848907 hasRelatedWork W1963814160 @default.
- W2000848907 hasRelatedWork W1980439982 @default.
- W2000848907 hasRelatedWork W2000848907 @default.
- W2000848907 hasRelatedWork W2055440597 @default.
- W2000848907 hasRelatedWork W2061011974 @default.
- W2000848907 hasRelatedWork W2087700041 @default.
- W2000848907 hasRelatedWork W2093146127 @default.
- W2000848907 hasRelatedWork W2412589631 @default.
- W2000848907 hasRelatedWork W3137934757 @default.
- W2000848907 hasVolume "6" @default.
- W2000848907 isParatext "false" @default.
- W2000848907 isRetracted "false" @default.
- W2000848907 magId "2000848907" @default.
- W2000848907 workType "article" @default.