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- W2000851650 abstract "Stroke is the second leading cause of death and the leading cause of disability in Western countries. More than 60% of patients remain disabled, 50% of patients suffer from hemiparesis and 30% remain unable to walk without assistance. The skeletal muscle is the main effector organ accountable for disability in stroke. This disability is primarily attributed to the brain lesion; however less attention is paid to structural, metabolic and functional alterations of muscle tissue after stroke. Hemiparetic stroke leads to various muscle abnormalities: A combination of denervation, disuse, inflammation, remodelling and spasticity accounts for a complex pattern of muscle tissue phenotype change and atrophy. The molecular mechanisms of muscle degradation after stroke are only incompletely understood. Reinnervation, fibre-type shift, disuse atrophy, and local inflammatory activation are only some of the key features yet to be explained. Only limited data is available today on clinical muscle changes after stroke that results from few studies in a mere 500 patients. Despite its importance for optimum post stroke recovery, stroke-related sarcopenia is not considered in current guidelines for stroke therapy or rehabilitation and measurement tools to address sarcopenia are infrequently used. This lack of robust evidence on muscle pathology after stroke and on treatment strategies needs to be addressed in an interdisciplinary integrated approach. This review provides an overview on current pathophysiologic insights and on clinical relevance of sarcopenia in stroke patients and on measurement tools to address the problem in the clinical setting." @default.
- W2000851650 created "2016-06-24" @default.
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- W2000851650 date "2013-12-01" @default.
- W2000851650 modified "2023-10-14" @default.
- W2000851650 title "Stroke induced Sarcopenia: Muscle wasting and disability after stroke" @default.
- W2000851650 cites W1572802944 @default.
- W2000851650 cites W1653442402 @default.
- W2000851650 cites W186716551 @default.
- W2000851650 cites W1877808272 @default.
- W2000851650 cites W1966262558 @default.
- W2000851650 cites W1966951994 @default.
- W2000851650 cites W1970516435 @default.
- W2000851650 cites W1971955996 @default.
- W2000851650 cites W1976550535 @default.
- W2000851650 cites W1983798831 @default.
- W2000851650 cites W1986401187 @default.
- W2000851650 cites W1986853827 @default.
- W2000851650 cites W1994612466 @default.
- W2000851650 cites W1998648979 @default.
- W2000851650 cites W1999968533 @default.
- W2000851650 cites W2003064100 @default.
- W2000851650 cites W2004032781 @default.
- W2000851650 cites W2007855286 @default.
- W2000851650 cites W2010239915 @default.
- W2000851650 cites W2018187251 @default.
- W2000851650 cites W2023049642 @default.
- W2000851650 cites W2023729390 @default.
- W2000851650 cites W2023971206 @default.
- W2000851650 cites W2024413668 @default.
- W2000851650 cites W2036855846 @default.
- W2000851650 cites W2038316924 @default.
- W2000851650 cites W2043202192 @default.
- W2000851650 cites W2044671618 @default.
- W2000851650 cites W2045461111 @default.
- W2000851650 cites W2045862896 @default.
- W2000851650 cites W2048798480 @default.
- W2000851650 cites W2048937882 @default.
- W2000851650 cites W2051446390 @default.
- W2000851650 cites W205495280 @default.
- W2000851650 cites W2056891285 @default.
- W2000851650 cites W2057228818 @default.
- W2000851650 cites W2060119724 @default.
- W2000851650 cites W2062247228 @default.
- W2000851650 cites W2063133122 @default.
- W2000851650 cites W2064052038 @default.
- W2000851650 cites W2081494312 @default.
- W2000851650 cites W2083683919 @default.
- W2000851650 cites W2085548226 @default.
- W2000851650 cites W2087635405 @default.
- W2000851650 cites W2096657471 @default.
- W2000851650 cites W2097950056 @default.
- W2000851650 cites W2103229054 @default.
- W2000851650 cites W2104846292 @default.
- W2000851650 cites W2106342888 @default.
- W2000851650 cites W2106569666 @default.
- W2000851650 cites W2106720958 @default.
- W2000851650 cites W2107826281 @default.
- W2000851650 cites W2110215578 @default.
- W2000851650 cites W2113347137 @default.
- W2000851650 cites W2114421292 @default.
- W2000851650 cites W2115385983 @default.
- W2000851650 cites W2116263214 @default.
- W2000851650 cites W2117743214 @default.
- W2000851650 cites W2118577904 @default.
- W2000851650 cites W2121713929 @default.
- W2000851650 cites W2124420617 @default.
- W2000851650 cites W2125117842 @default.
- W2000851650 cites W2126725714 @default.
- W2000851650 cites W2129122538 @default.
- W2000851650 cites W2129769979 @default.
- W2000851650 cites W2133660074 @default.
- W2000851650 cites W2133764408 @default.
- W2000851650 cites W2137687978 @default.
- W2000851650 cites W2143149622 @default.
- W2000851650 cites W2146571284 @default.
- W2000851650 cites W2150498597 @default.
- W2000851650 cites W2151277084 @default.
- W2000851650 cites W2162096099 @default.
- W2000851650 cites W2165447041 @default.
- W2000851650 cites W2167602265 @default.
- W2000851650 cites W2276904803 @default.
- W2000851650 cites W2401673499 @default.
- W2000851650 cites W2949679206 @default.
- W2000851650 cites W4211259557 @default.
- W2000851650 cites W4292172722 @default.
- W2000851650 doi "https://doi.org/10.1016/j.ijcard.2013.10.031" @default.
- W2000851650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24231058" @default.
- W2000851650 hasPublicationYear "2013" @default.
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