Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000856916> ?p ?o ?g. }
- W2000856916 endingPage "256" @default.
- W2000856916 startingPage "249" @default.
- W2000856916 abstract "The effect of vitamin C supplementation on hepatic cytochrome P450 expression was investigated in streptozotocin (STZ) diabetic male Wistar Albino rats. STZ-treated rats displayed the usual characteristics of diabetes including; hyperphagia, polydipsia, decreased body weight gain and also the increased expression and activity of hepatic CYP1A, 2B, 2E and 4A proteins. Vitamin C administration in drinking water (2% w/v) was associated with significant decreases in the levels of hyperglycaemia (P < 0.05), glycosylated haemoglobin (P < 0.05), hyperiipidaemia (P < 0.001), and hyperketonaemia (P < 0.001) associated with STZ-diabetes. Vitamin C-treatment selectively reduced the activity and expression of CYP2E proteins (P < 0.001). These effects on CYP2E expression may be mediated by the reduced levels of circulating ketone bodies, however, a direct effect on CYP2E expression in diabetes cannot be discounted." @default.
- W2000856916 created "2016-06-24" @default.
- W2000856916 creator A5031869747 @default.
- W2000856916 creator A5047564185 @default.
- W2000856916 creator A5075620817 @default.
- W2000856916 creator A5084658538 @default.
- W2000856916 creator A5087281525 @default.
- W2000856916 date "1996-12-01" @default.
- W2000856916 modified "2023-09-26" @default.
- W2000856916 title "Effect of vitamin C supplementation on hepatic cytochrome P450 mixed-function oxidase activity in streptozotocin-diabetic rats" @default.
- W2000856916 cites W1269656245 @default.
- W2000856916 cites W1483556659 @default.
- W2000856916 cites W1543862651 @default.
- W2000856916 cites W1545770421 @default.
- W2000856916 cites W1584529073 @default.
- W2000856916 cites W1775749144 @default.
- W2000856916 cites W1951469402 @default.
- W2000856916 cites W1968510907 @default.
- W2000856916 cites W1970267020 @default.
- W2000856916 cites W1976193506 @default.
- W2000856916 cites W1976837599 @default.
- W2000856916 cites W1984170856 @default.
- W2000856916 cites W1984232613 @default.
- W2000856916 cites W1984526747 @default.
- W2000856916 cites W1996143925 @default.
- W2000856916 cites W1997426006 @default.
- W2000856916 cites W1998614770 @default.
- W2000856916 cites W2019039478 @default.
- W2000856916 cites W2032702940 @default.
- W2000856916 cites W2057179651 @default.
- W2000856916 cites W2057792822 @default.
- W2000856916 cites W2059522525 @default.
- W2000856916 cites W2060383676 @default.
- W2000856916 cites W2088181773 @default.
- W2000856916 cites W2100187630 @default.
- W2000856916 cites W2100837269 @default.
- W2000856916 cites W2154774609 @default.
- W2000856916 cites W2166838238 @default.
- W2000856916 cites W2166848521 @default.
- W2000856916 cites W2168237329 @default.
- W2000856916 cites W2343309659 @default.
- W2000856916 doi "https://doi.org/10.1016/s0378-4274(96)03822-2" @default.
- W2000856916 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9001594" @default.
- W2000856916 hasPublicationYear "1996" @default.
- W2000856916 type Work @default.
- W2000856916 sameAs 2000856916 @default.
- W2000856916 citedByCount "17" @default.
- W2000856916 countsByYear W20008569162014 @default.
- W2000856916 countsByYear W20008569162015 @default.
- W2000856916 countsByYear W20008569162019 @default.
- W2000856916 countsByYear W20008569162023 @default.
- W2000856916 crossrefType "journal-article" @default.
- W2000856916 hasAuthorship W2000856916A5031869747 @default.
- W2000856916 hasAuthorship W2000856916A5047564185 @default.
- W2000856916 hasAuthorship W2000856916A5075620817 @default.
- W2000856916 hasAuthorship W2000856916A5084658538 @default.
- W2000856916 hasAuthorship W2000856916A5087281525 @default.
- W2000856916 hasConcept C126322002 @default.
- W2000856916 hasConcept C134018914 @default.
- W2000856916 hasConcept C181199279 @default.
- W2000856916 hasConcept C185592680 @default.
- W2000856916 hasConcept C2776940978 @default.
- W2000856916 hasConcept C2779280383 @default.
- W2000856916 hasConcept C2779624480 @default.
- W2000856916 hasConcept C2780022331 @default.
- W2000856916 hasConcept C31532488 @default.
- W2000856916 hasConcept C38485361 @default.
- W2000856916 hasConcept C526171541 @default.
- W2000856916 hasConcept C55493867 @default.
- W2000856916 hasConcept C555293320 @default.
- W2000856916 hasConcept C62231903 @default.
- W2000856916 hasConcept C71924100 @default.
- W2000856916 hasConceptScore W2000856916C126322002 @default.
- W2000856916 hasConceptScore W2000856916C134018914 @default.
- W2000856916 hasConceptScore W2000856916C181199279 @default.
- W2000856916 hasConceptScore W2000856916C185592680 @default.
- W2000856916 hasConceptScore W2000856916C2776940978 @default.
- W2000856916 hasConceptScore W2000856916C2779280383 @default.
- W2000856916 hasConceptScore W2000856916C2779624480 @default.
- W2000856916 hasConceptScore W2000856916C2780022331 @default.
- W2000856916 hasConceptScore W2000856916C31532488 @default.
- W2000856916 hasConceptScore W2000856916C38485361 @default.
- W2000856916 hasConceptScore W2000856916C526171541 @default.
- W2000856916 hasConceptScore W2000856916C55493867 @default.
- W2000856916 hasConceptScore W2000856916C555293320 @default.
- W2000856916 hasConceptScore W2000856916C62231903 @default.
- W2000856916 hasConceptScore W2000856916C71924100 @default.
- W2000856916 hasIssue "3" @default.
- W2000856916 hasLocation W20008569161 @default.
- W2000856916 hasLocation W20008569162 @default.
- W2000856916 hasOpenAccess W2000856916 @default.
- W2000856916 hasPrimaryLocation W20008569161 @default.
- W2000856916 hasRelatedWork W1995071802 @default.
- W2000856916 hasRelatedWork W1998113603 @default.
- W2000856916 hasRelatedWork W2005354325 @default.
- W2000856916 hasRelatedWork W2011709829 @default.
- W2000856916 hasRelatedWork W2055342276 @default.
- W2000856916 hasRelatedWork W2092993950 @default.