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• W2000858137 abstract "ABSTRACT Recovery of plants from virus-induced symptoms is often described as a consequence of RNA silencing, an antiviral defense mechanism. For example, recovery of Nicotiana clevelandii from a nepovirus (tomato black ring virus) is associated with a decreased viral RNA concentration and sequence-specific resistance to further virus infection. In this study, we have characterized the interaction of another nepovirus, tomato ringspot virus (ToRSV), with host defense responses during symptom induction and subsequent recovery. Early in infection, ToRSV induced a necrotic phenotype in Nicotiana benthamiana that showed characteristics typical of a hypersensitive response. RNA silencing was also activated during ToRSV infection, as evidenced by the presence of ToRSV-derived small interfering RNAs (siRNAs) that could direct degradation of ToRSV sequences introduced into sensor constructs. Surprisingly, disappearance of symptoms was not accompanied by a commensurate reduction in viral RNA levels. The stability of ToRSV RNA after recovery was also observed in N. clevelandii and Cucumis sativus and in N. benthamiana plants carrying a functional RNA-dependent RNA polymerase 1 ortholog from Medicago truncatula . In experiments with a reporter transgene (green fluorescent protein), ToRSV did not suppress the initiation or maintenance of transgene silencing, although the movement of the silencing signal was partially hindered. Our results demonstrate that although RNA silencing is active during recovery, reduction of virus titer is not required for the initiation of this phenotype. This scenario adds an unforeseen layer of complexity to the interaction of nepoviruses with the host RNA silencing machinery. The possibility that viral proteins, viral RNAs, and/or virus-derived siRNAs inactivate host defense responses is discussed." @default.
• W2000858137 created "2016-06-24" @default.
• W2000858137 creator A5062625688 @default.
• W2000858137 creator A5087847164 @default.
• W2000858137 creator A5088709156 @default.
• W2000858137 date "2007-11-15" @default.
• W2000858137 modified "2023-10-04" @default.
• W2000858137 title "Recovery of <i>Nicotiana benthamiana</i> Plants from a Necrotic Response Induced by a Nepovirus Is Associated with RNA Silencing but Not with Reduced Virus Titer" @default.
• W2000858137 cites W1542452066 @default.
• W2000858137 cites W1915879975 @default.
• W2000858137 cites W1968291875 @default.
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• W2000858137 cites W1978947159 @default.
• W2000858137 cites W1979965542 @default.
• W2000858137 cites W1987029108 @default.
• W2000858137 cites W1987235162 @default.
• W2000858137 cites W1989174148 @default.
• W2000858137 cites W1996065891 @default.
• W2000858137 cites W1998469642 @default.
• W2000858137 cites W2006101755 @default.
• W2000858137 cites W2015093208 @default.
• W2000858137 cites W2018484899 @default.
• W2000858137 cites W2032223524 @default.
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• W2000858137 cites W2038009600 @default.
• W2000858137 cites W2040712240 @default.
• W2000858137 cites W2045385949 @default.
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• W2000858137 cites W2048078120 @default.
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• W2000858137 doi "https://doi.org/10.1128/jvi.01192-07" @default.
• W2000858137 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2168989" @default.
• W2000858137 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17728227" @default.
• W2000858137 hasPublicationYear "2007" @default.
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