Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000867098> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2000867098 abstract "A rare, inborn error of metabolism is frequently referred to as nature's experiment. By adding experimental touches of his own, the investigator may gain insights not only into the mechanisms of a particular genetic disorder, but also into related physiologic derangements underlying other, more common conditions. We owe much of our knowledge of physiology and pathophysiology to studies of genetic rarities. One such genetic disease is progeria . Inherited as an autosomal recessive trait, this disease is characterized by precocious senility. The afflicted child with his wizened face, dwarfed stature, and the general appearance of senility usually dies of coronary heart disease during the first or second decade of life. The stamp of senescence is imprinted in various cells by deposits of lipofuchsin, and in the myocardium by focal fibrosis. Can this disorder, which telescopes a life-span into the brief period of a dozen or so years, shed some light on" @default.
- W2000867098 created "2016-06-24" @default.
- W2000867098 creator A5090738172 @default.
- W2000867098 date "1973-12-24" @default.
- W2000867098 modified "2023-09-28" @default.
- W2000867098 title "Nature's Experiment in Unnatural Aging" @default.
- W2000867098 cites W159681246 @default.
- W2000867098 cites W2009125778 @default.
- W2000867098 cites W2023972498 @default.
- W2000867098 cites W2095153932 @default.
- W2000867098 cites W2145066998 @default.
- W2000867098 doi "https://doi.org/10.1001/jama.1973.03230130053020" @default.
- W2000867098 hasPublicationYear "1973" @default.
- W2000867098 type Work @default.
- W2000867098 sameAs 2000867098 @default.
- W2000867098 citedByCount "2" @default.
- W2000867098 crossrefType "journal-article" @default.
- W2000867098 hasAuthorship W2000867098A5090738172 @default.
- W2000867098 hasConcept C104317684 @default.
- W2000867098 hasConcept C106934330 @default.
- W2000867098 hasConcept C142724271 @default.
- W2000867098 hasConcept C187212893 @default.
- W2000867098 hasConcept C199360897 @default.
- W2000867098 hasConcept C2777871287 @default.
- W2000867098 hasConcept C2778465436 @default.
- W2000867098 hasConcept C2778908642 @default.
- W2000867098 hasConcept C2779134260 @default.
- W2000867098 hasConcept C2909947164 @default.
- W2000867098 hasConcept C2988516024 @default.
- W2000867098 hasConcept C3020341036 @default.
- W2000867098 hasConcept C41008148 @default.
- W2000867098 hasConcept C42407357 @default.
- W2000867098 hasConcept C54355233 @default.
- W2000867098 hasConcept C71924100 @default.
- W2000867098 hasConcept C74909509 @default.
- W2000867098 hasConcept C86803240 @default.
- W2000867098 hasConceptScore W2000867098C104317684 @default.
- W2000867098 hasConceptScore W2000867098C106934330 @default.
- W2000867098 hasConceptScore W2000867098C142724271 @default.
- W2000867098 hasConceptScore W2000867098C187212893 @default.
- W2000867098 hasConceptScore W2000867098C199360897 @default.
- W2000867098 hasConceptScore W2000867098C2777871287 @default.
- W2000867098 hasConceptScore W2000867098C2778465436 @default.
- W2000867098 hasConceptScore W2000867098C2778908642 @default.
- W2000867098 hasConceptScore W2000867098C2779134260 @default.
- W2000867098 hasConceptScore W2000867098C2909947164 @default.
- W2000867098 hasConceptScore W2000867098C2988516024 @default.
- W2000867098 hasConceptScore W2000867098C3020341036 @default.
- W2000867098 hasConceptScore W2000867098C41008148 @default.
- W2000867098 hasConceptScore W2000867098C42407357 @default.
- W2000867098 hasConceptScore W2000867098C54355233 @default.
- W2000867098 hasConceptScore W2000867098C71924100 @default.
- W2000867098 hasConceptScore W2000867098C74909509 @default.
- W2000867098 hasConceptScore W2000867098C86803240 @default.
- W2000867098 hasLocation W20008670981 @default.
- W2000867098 hasOpenAccess W2000867098 @default.
- W2000867098 hasPrimaryLocation W20008670981 @default.
- W2000867098 hasRelatedWork W134867575 @default.
- W2000867098 hasRelatedWork W1489456073 @default.
- W2000867098 hasRelatedWork W1574620438 @default.
- W2000867098 hasRelatedWork W1976272757 @default.
- W2000867098 hasRelatedWork W2068723807 @default.
- W2000867098 hasRelatedWork W2087807503 @default.
- W2000867098 hasRelatedWork W2171489517 @default.
- W2000867098 hasRelatedWork W2189440127 @default.
- W2000867098 hasRelatedWork W2221835116 @default.
- W2000867098 hasRelatedWork W2398109690 @default.
- W2000867098 hasRelatedWork W2422990629 @default.
- W2000867098 hasRelatedWork W2975946852 @default.
- W2000867098 hasRelatedWork W62761171 @default.
- W2000867098 isParatext "false" @default.
- W2000867098 isRetracted "false" @default.
- W2000867098 magId "2000867098" @default.
- W2000867098 workType "article" @default.