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- W2000870852 abstract "<h2>Abstract</h2> Objective: To investigate preoperative clinical conditions and/or intraoperative physiologic variables related to jugular venous oxygen saturation (Sj0<sub>2</sub>) during cardiopulmonary bypass (CPB). Design: Prospective study. Setting: General hospital, single institution. Participants: One hundred forty patients (52 women, 88 men) who underwent coronary artery bypass grafting. Measurements and Main Results: The authors measured Sj0<sub>2</sub> at five times during surgery. Multiple stepwise regression analysis showed a significant correlation of SjO<sub>2</sub> with (1) arterial carbon dioxide partial pressure (PaCO<sub>2</sub>) before CPB (standard regression coefficient [(SC)] = 0.435), (2) cerebral perfusion pressure (CPP) during initiation of CPB (SC = 0.259), (3) PaCO<sub>2</sub>, tympanic temperature (TT), bubble oxygenator, and cerebral small infarctions (CSIs) during hypothermic CPB (SC = 0.507, −0.237, −0.192, and −0.189, respectively), (4) CPP, PaCO<sub>2</sub>, CSIs, and bubble oxygenator during rewarming (SC = 0.476, 0.294, −0.220, and −0.189, respectively), and (5) PaCO<sub>2</sub> after CPB (SC = 0.480; <i>p</i> < 0.01). Correlation coefficients between Sj0<sub>2</sub> and CPP during rewarming were 0.40 (0.46 without CSI and 0.37 with CSI; <i>p</i> < 0.01). These results indicate that the relationship between CPP and SjO<sub>2</sub> was significant in patients with CPP less than 40 mmHg during rewarming. Conclusion: During rewarming, when cerebral perfusion and oxygen demand change abruptly, but not during stable hypothermic CPB, CPP was a significant factor related to SjO<sub>2</sub>." @default.
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- W2000870852 date "1999-04-01" @default.
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- W2000870852 title "Analysis of factors related to jugular venous oxygen saturation during cardiopulmonary bypass" @default.
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- W2000870852 doi "https://doi.org/10.1016/s1053-0770(99)90080-0" @default.
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