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- W2000871388 abstract "We have studied the effect of modafinil and amphetamine, two waking drugs, on the sleep-wake cycle of Sprague-Dawley rat. Both modafinil (64 or 128 mg/kg) and amphetamine (2.5 or 5 mg/kg) cause a dose dependent increase in wakefulness. However, amphetamine wakefulness is followed by a paradoxical sleep rebound on the injection day, whereas modafinil does not produce this effect. In modafinil-treated rats, the sleep pattern on the post-injection day is similar to that of controls, while that of amphetamine-treated rats is modified." @default.
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- W2000871388 date "1995-04-01" @default.
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- W2000871388 title "Awakening properties of modafinil without paradoxical sleep rebound: comparative study with amphetamine in the rat" @default.
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- W2000871388 doi "https://doi.org/10.1016/0304-3940(95)11448-6" @default.
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