FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000871802> ?p ?o ?g. }

• W2000871802 endingPage "795" @default.
• W2000871802 startingPage "789" @default.
• W2000871802 abstract "An examination has been made of the binding, both in vitro and in vivo, of the benzo(a)pyrene (BP) adduct to DNA components of differing sequence complexity. Annealing was performed at low renaturation temperatures in the presence of high concentrations of formamide to minimize hydrocarbon-induced depurination. BHK-DNA was modified in vitro using a tritiated derivative of the ultimate carcinogenic metabolite of BP, 7alpha,8beta-di-hydroxy-9beta,10beta-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene (BPDE). Co-renaturation of this modfied DNA with [14C]-thymidine-labelled BHK-DNA demonstrated that the hydrocarbon adduct did not interfere with strand annealing and showed that the BP adduct was distributed randomly throughout all DNA sequence classes. However, when the DNA of cells in culture was modified by [3H]BP, following metabolic activation, and mixed with [14C]-thymidine-labelled DNA, a small but reproducible difference in the renaturation of the two labels was found. This difference in renaturation profiles was not due to base-compositional effects since a similar result was found when the alternate 14C-label was present in guanine bases, the principal site of BP modification. The small difference in the renaturation of the two radioactive labels indicated an enrichment of the hydrocarbon on the most rapidly-renaturing sequence components (the palindromic and highly repetitive sequences) where it amounted to between 19 and 64% increased modification." @default.
• W2000871802 created "2016-06-24" @default.
• W2000871802 creator A5010521840 @default.
• W2000871802 creator A5068213118 @default.
• W2000871802 date "1980-06-15" @default.
• W2000871802 modified "2023-09-27" @default.
• W2000871802 title "The binding of benzo(a)pyrene to DNA components of differing sequence complexity" @default.
• W2000871802 cites W141454995 @default.
• W2000871802 cites W1600718860 @default.
• W2000871802 cites W1966750352 @default.
• W2000871802 cites W1972248958 @default.
• W2000871802 cites W1973001100 @default.
• W2000871802 cites W1976994354 @default.
• W2000871802 cites W1985606919 @default.
• W2000871802 cites W1986683189 @default.
• W2000871802 cites W1993557939 @default.
• W2000871802 cites W1994415652 @default.
• W2000871802 cites W1997681444 @default.
• W2000871802 cites W2010916267 @default.
• W2000871802 cites W2012766496 @default.
• W2000871802 cites W2024778127 @default.
• W2000871802 cites W2034581891 @default.
• W2000871802 cites W2034886856 @default.
• W2000871802 cites W2038461948 @default.
• W2000871802 cites W2039434232 @default.
• W2000871802 cites W2053992693 @default.
• W2000871802 cites W2057128698 @default.
• W2000871802 cites W2062241257 @default.
• W2000871802 cites W2064211730 @default.
• W2000871802 cites W2069332757 @default.
• W2000871802 cites W2071363055 @default.
• W2000871802 cites W2076096295 @default.
• W2000871802 cites W2078965802 @default.
• W2000871802 cites W2085064863 @default.
• W2000871802 cites W2139046279 @default.
• W2000871802 doi "https://doi.org/10.1002/ijc.2910250615" @default.
• W2000871802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14768709" @default.
• W2000871802 hasPublicationYear "1980" @default.
• W2000871802 type Work @default.
• W2000871802 sameAs 2000871802 @default.
• W2000871802 citedByCount "8" @default.
• W2000871802 countsByYear W20008718022013 @default.
• W2000871802 crossrefType "journal-article" @default.
• W2000871802 hasAuthorship W2000871802A5010521840 @default.
• W2000871802 hasAuthorship W2000871802A5068213118 @default.
• W2000871802 hasConcept C104317684 @default.
• W2000871802 hasConcept C108204754 @default.
• W2000871802 hasConcept C114246631 @default.
• W2000871802 hasConcept C129312508 @default.
• W2000871802 hasConcept C178790620 @default.
• W2000871802 hasConcept C185592680 @default.
• W2000871802 hasConcept C2776023528 @default.
• W2000871802 hasConcept C2777108182 @default.
• W2000871802 hasConcept C2777538855 @default.
• W2000871802 hasConcept C2778301229 @default.
• W2000871802 hasConcept C2778951431 @default.
• W2000871802 hasConcept C34737976 @default.
• W2000871802 hasConcept C44667518 @default.
• W2000871802 hasConcept C512185932 @default.
• W2000871802 hasConcept C552990157 @default.
• W2000871802 hasConcept C55493867 @default.
• W2000871802 hasConcept C71240020 @default.
• W2000871802 hasConcept C76557 @default.
• W2000871802 hasConcept C98108389 @default.
• W2000871802 hasConceptScore W2000871802C104317684 @default.
• W2000871802 hasConceptScore W2000871802C108204754 @default.
• W2000871802 hasConceptScore W2000871802C114246631 @default.
• W2000871802 hasConceptScore W2000871802C129312508 @default.
• W2000871802 hasConceptScore W2000871802C178790620 @default.
• W2000871802 hasConceptScore W2000871802C185592680 @default.
• W2000871802 hasConceptScore W2000871802C2776023528 @default.
• W2000871802 hasConceptScore W2000871802C2777108182 @default.
• W2000871802 hasConceptScore W2000871802C2777538855 @default.
• W2000871802 hasConceptScore W2000871802C2778301229 @default.
• W2000871802 hasConceptScore W2000871802C2778951431 @default.
• W2000871802 hasConceptScore W2000871802C34737976 @default.
• W2000871802 hasConceptScore W2000871802C44667518 @default.
• W2000871802 hasConceptScore W2000871802C512185932 @default.
• W2000871802 hasConceptScore W2000871802C552990157 @default.
• W2000871802 hasConceptScore W2000871802C55493867 @default.
• W2000871802 hasConceptScore W2000871802C71240020 @default.
• W2000871802 hasConceptScore W2000871802C76557 @default.
• W2000871802 hasConceptScore W2000871802C98108389 @default.
• W2000871802 hasIssue "6" @default.
• W2000871802 hasLocation W20008718021 @default.
• W2000871802 hasLocation W20008718022 @default.
• W2000871802 hasOpenAccess W2000871802 @default.
• W2000871802 hasPrimaryLocation W20008718021 @default.
• W2000871802 hasRelatedWork W1964025682 @default.
• W2000871802 hasRelatedWork W1972397196 @default.
• W2000871802 hasRelatedWork W1976891699 @default.
• W2000871802 hasRelatedWork W1977280342 @default.
• W2000871802 hasRelatedWork W1987389021 @default.
• W2000871802 hasRelatedWork W1997248328 @default.
• W2000871802 hasRelatedWork W2000871802 @default.
• W2000871802 hasRelatedWork W2086812285 @default.
• W2000871802 hasRelatedWork W2226624016 @default.
• W2000871802 hasRelatedWork W2414596920 @default.

• next