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- W2000872377 endingPage "1198" @default.
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- W2000872377 abstract "In the last 13 years, three gene therapy trials for the treatment of alpha-1 antitrypsin deficiency have been conducted. The first trial delivered plasmid encoding the alpha-1 antitrypsin cDNA to the nasal epithelium using cationic liposomes. The last two trials delivered recombinant adeno-associated vectors encoding the alpha-1 antitrypsin cDNA by intramuscular injection. In this review, the progress of ongoing clinical trials and new gene therapy technologies is discussed." @default.
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- W2000872377 date "2007-09-01" @default.
- W2000872377 modified "2023-10-10" @default.
- W2000872377 title "The promise of gene therapy for the treatment of α-1 antitrypsin deficiency" @default.
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- W2000872377 doi "https://doi.org/10.2217/14622416.8.9.1191" @default.
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