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• W2000872486 abstract "The alkaloid extract and five alkaloids isolated from subterranean stem bark of Duguetia furfuracea (Annonaceae) were investigated for the following activities: antitumoral, trypanocidal and leishmanicidal. Dicentrinone showed weak cytotoxicity, but it had the strongest leishmanicidal activity (IC50 0.01 μM). Duguetine and duguetine β-N-oxide caused considerable antitumoral activity in every cell lines evaluated, although duguetine was more active against trypomastigote forms (IC50 9.32 μM) than other alkaloids tested." @default.
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• W2000872486 date "2009-11-01" @default.
• W2000872486 modified "2023-10-11" @default.
• W2000872486 title "The antitumoral, trypanocidal and antileishmanial activities of extract and alkaloids isolated from Duguetia furfuracea" @default.
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• W2000872486 doi "https://doi.org/10.1016/j.phymed.2009.03.019" @default.
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