Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000874747> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2000874747 endingPage "717" @default.
- W2000874747 startingPage "712" @default.
- W2000874747 abstract "Chinese hamster ovary (CHO) cells used in many transfection studies have been found to endogenously express channels permeable to monovalent cations, but not to divalent cations. In the presence of intracellular Ca(2+), 23-pS channel with a linear current-voltage (I-V) relationship could be frequently observed in inside-out patches but not in cell-attached patches. The open probability was voltage-dependent, which is higher at positive potentials. The channel was dose-dependently activated by relatively high level of Ca(2+) (EC(50)=1.04+/-0.08 mM), and sensitively inhibited by 100 microM ATP, ADP, AMP, and 1mM spermine. However, ruthenium red (2 microM) had no effect. Reverse transcript polymerase chain reaction (RT-PCR) supported the presence of mRNA encoding TRPM4b channel protein. Western blot assay finally confirmed the presence of this channel protein in membrane fraction of CHO cells. These results provide evidence that CHO cells express an endogenous TRPM4b-like channel, and thereby can be used as a tool to study de novo regulation/modulation of TRPM4 channel." @default.
- W2000874747 created "2016-06-24" @default.
- W2000874747 creator A5000694666 @default.
- W2000874747 creator A5002369637 @default.
- W2000874747 creator A5016539318 @default.
- W2000874747 creator A5025762023 @default.
- W2000874747 creator A5038460242 @default.
- W2000874747 creator A5055830493 @default.
- W2000874747 date "2008-05-01" @default.
- W2000874747 modified "2023-10-16" @default.
- W2000874747 title "Endogenous TRPM4-like channel in Chinese hamster ovary (CHO) cells" @default.
- W2000874747 cites W1980092005 @default.
- W2000874747 cites W1983615879 @default.
- W2000874747 cites W1985409918 @default.
- W2000874747 cites W2015200345 @default.
- W2000874747 cites W2029087863 @default.
- W2000874747 cites W2095955574 @default.
- W2000874747 cites W2111730001 @default.
- W2000874747 cites W2112767644 @default.
- W2000874747 cites W2117494644 @default.
- W2000874747 cites W2133371028 @default.
- W2000874747 cites W2136349508 @default.
- W2000874747 cites W2156981723 @default.
- W2000874747 cites W2164838292 @default.
- W2000874747 doi "https://doi.org/10.1016/j.bbrc.2008.02.081" @default.
- W2000874747 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18307979" @default.
- W2000874747 hasPublicationYear "2008" @default.
- W2000874747 type Work @default.
- W2000874747 sameAs 2000874747 @default.
- W2000874747 citedByCount "13" @default.
- W2000874747 countsByYear W20008747472012 @default.
- W2000874747 countsByYear W20008747472014 @default.
- W2000874747 countsByYear W20008747472015 @default.
- W2000874747 countsByYear W20008747472016 @default.
- W2000874747 countsByYear W20008747472017 @default.
- W2000874747 countsByYear W20008747472021 @default.
- W2000874747 countsByYear W20008747472022 @default.
- W2000874747 crossrefType "journal-article" @default.
- W2000874747 hasAuthorship W2000874747A5000694666 @default.
- W2000874747 hasAuthorship W2000874747A5002369637 @default.
- W2000874747 hasAuthorship W2000874747A5016539318 @default.
- W2000874747 hasAuthorship W2000874747A5025762023 @default.
- W2000874747 hasAuthorship W2000874747A5038460242 @default.
- W2000874747 hasAuthorship W2000874747A5055830493 @default.
- W2000874747 hasConcept C104317684 @default.
- W2000874747 hasConcept C12554922 @default.
- W2000874747 hasConcept C153911025 @default.
- W2000874747 hasConcept C16613235 @default.
- W2000874747 hasConcept C170493617 @default.
- W2000874747 hasConcept C175656101 @default.
- W2000874747 hasConcept C181911157 @default.
- W2000874747 hasConcept C185592680 @default.
- W2000874747 hasConcept C2776415932 @default.
- W2000874747 hasConcept C54009773 @default.
- W2000874747 hasConcept C55493867 @default.
- W2000874747 hasConcept C79879829 @default.
- W2000874747 hasConcept C86803240 @default.
- W2000874747 hasConceptScore W2000874747C104317684 @default.
- W2000874747 hasConceptScore W2000874747C12554922 @default.
- W2000874747 hasConceptScore W2000874747C153911025 @default.
- W2000874747 hasConceptScore W2000874747C16613235 @default.
- W2000874747 hasConceptScore W2000874747C170493617 @default.
- W2000874747 hasConceptScore W2000874747C175656101 @default.
- W2000874747 hasConceptScore W2000874747C181911157 @default.
- W2000874747 hasConceptScore W2000874747C185592680 @default.
- W2000874747 hasConceptScore W2000874747C2776415932 @default.
- W2000874747 hasConceptScore W2000874747C54009773 @default.
- W2000874747 hasConceptScore W2000874747C55493867 @default.
- W2000874747 hasConceptScore W2000874747C79879829 @default.
- W2000874747 hasConceptScore W2000874747C86803240 @default.
- W2000874747 hasIssue "2" @default.
- W2000874747 hasLocation W20008747471 @default.
- W2000874747 hasLocation W20008747472 @default.
- W2000874747 hasOpenAccess W2000874747 @default.
- W2000874747 hasPrimaryLocation W20008747471 @default.
- W2000874747 hasRelatedWork W2053393868 @default.
- W2000874747 hasRelatedWork W2057291960 @default.
- W2000874747 hasRelatedWork W2359175313 @default.
- W2000874747 hasRelatedWork W2363104495 @default.
- W2000874747 hasRelatedWork W2370064380 @default.
- W2000874747 hasRelatedWork W2378943006 @default.
- W2000874747 hasRelatedWork W2387801567 @default.
- W2000874747 hasRelatedWork W2442342451 @default.
- W2000874747 hasRelatedWork W2997937149 @default.
- W2000874747 hasRelatedWork W2117818578 @default.
- W2000874747 hasVolume "369" @default.
- W2000874747 isParatext "false" @default.
- W2000874747 isRetracted "false" @default.
- W2000874747 magId "2000874747" @default.
- W2000874747 workType "article" @default.